Global ETD Search
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Showing 1 to 5 of 5 for “"Oxygen extraction fraction"”.
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MRI based cerebral oxygenation measures in humans : technical development for use across lifespan
MRI based cerebral oxygenation measures could enable brain-centered clinical care and improve understanding of brain energy use throughout human development. We made technical improvements to two MR oxygenation imaging techniques, and explored the concordance between various methods to quantify the …
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Brain segmentation using endogenous contrast mechanism using breath holding fMRI signal for tissue characterization
… blood flow (CBF), cerebral blood volume (CBV), oxygen extraction fraction (OEF), and other physiological factors are then estimated and differences between diseased regions and healthy regions are then elucidated.
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Improved accuracy in susceptibility-based OEF measurements by mitigation of partial-volume effects via combined magnitude and phase reconstruction
Regional quantitative Oxygen Extraction Fraction (OEF) values can only be reliable obtained from blood vessels larger than the acquisition voxel size. Blood vessels beyond this limit produce unreliable measurements due to partial-volume effects. We demonstrate a method for obtaining more reliable …
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Magnetic resonance imaging of the cerebral metabolic rate of oxygen (CMRO₂)
Oxygen consumption is an essential process of the functioning brain. The rate at which the brain consumes oxygen is known as the cerebral metabolic rate of oxygen (CMRO₂). CMRO₂ is intimately related to brain health and function, and will change in settings of disease and functional activation. …
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Development, testing, and application of quantitative oxygenation imaging from magnetic susceptibility by MRI
The healthy brain consumes 20% of total oxygen used by the body under normal conditions. Continuous oxygen delivery to neural tissue is needed to maintain normal brain function and viability. Reliable measurements of brain oxygenation can provide critical information to diagnose and manage diseases …