Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"Oxygen Consumption Rate"”.
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Transient oxygen consumption rate measurements with the BDT̳M̳ oxygen biosensor system
Oxygen consumption rate (OCR) is a reliable indicator of tissue health. Recently, the OCR of isolated human islets has been shown to predict transplant outcome in diabetic mice. The Oxygen Biosensor System (OBS) is a high-throughput, convenient assay that indirectly measures oxygen consumption by …
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Effects of Pan-I genotype and family cross on oxygen consumption rate among juvenile Atlantic Cod (Gadus morhua)
… environmental temperatures. We compared the oxygen consumption rate (VO2/M) of juvenile Atlantic cod from both different family crosses and with different Pan-I genotypes acclimated to 4ºC, 8ºC and 12ºC and when exposed to an acute thermal challenge. No differences were found between genotype …
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Swimming behavior and energetics of sharks
… beats.s-1. Measurement of swimming speed and rate of vertical movement during dives permits calculation of angles of ascent and descent. For 84 dives deeper than 50 m, the descent angle averaged 8.0 ± 0.7 degrees from the horizontal while the ascent angle was 6.4 ± 0.5 degrees. Tailbeat …
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The effect of iron metabolism on palmitate-induced INS-1 cell death
… (LIP) 29 11. Aconitase activity assay 29 12. Oxygen consumption rate (OCR) 30 13. PA uptake 31 14. Quantitation of insulin 31 15. Immunocytochemistry 32 16. Statistics 32 Ⅲ. RESULTS [Part I] 36 A. Palmitate treatment reduces intracellular iron level in INS-1 beta cell. 36 B. Iron depletion and …
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The electron transport chains of Neisseria meningitidis
… Oxidation of c-type and b-type cytochromes by oxygen was observed in both cells grown under aerobic and denitrifying conditions, whereas oxidation of cytochromes by nitrite was only seen in cells grown under denitrifying conditions, and the predominant oxidizable cytochromes were b-type. These …
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The COD/VSS ratio of the volatile solids in the activated sludge process
… 20°C treating a raw domestic effluent were operated and tested. These experiments indicated a slight increase in the COD/VSS ratio at a 3 day sludge age at 12°C (relative to the other units) but insufficient to explain the discrepancies in the COD balances observed by Dold et al. (1980). During …
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Defect of Mitochondrial Translation Machinery Enhances Hepatoma Cell Invasiveness
… 1. Cell cultures, drug treatment and cell growth rate 4 2. Reverse transcription-polymerase chain reaction (RT-PCR) 4 3. Endogenous cellular oxygen consumption rate 5 4. Estimation of intracellular and mitochondrial ROS level 5 5. Total genomic DNA isolation and sequencing of mitochondrial DNA …
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Influence of Physical Stress, Sex, and Body Size on Metabolic Rates of Ozark Zigzag Salamanders, Plethodon Angusticlavius
… responses. One response is an increase in oxygen consumption rate. Individuals were physically stressed to simulate a predatory attack, and oxygen consumption was measured following stress using a constant respirometry apparatus. For large salamanders (SVL ≥ 32 mm), stressed individuals had …
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Exertion therapy for the mentally subnormal child.
… participated in the 30-week programme. Heart rate at rest, heart rate at sub minimal workload and maximal oxygen consumption rate estimates served as measures of physical fitness. Changes in intellectual and social functioning were assessed by means of the Vineland Social Maturity Scale, Old …
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Arsenic Toxicity and Altered Mitochondrial Bioenergetics in Response to Oxidative Stress
… effects is crucial to developing preventative strategies and more effective treatments for individuals with long term exposure to arsenic compounds. This thesis outlines the epidemiological evidence for arsenic-linked diseases as well as the current understanding of arsenic metabolism and the …
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Regulation of mitochondrial respiration by LDHB suppression in hepatoma cell lines
… suppressed by siRNA-mediated knockdown, cellular oxygen consumption rate was significantly decreased without clear decrease in expressions of respiratory proteins. These results imply that LDHB suppression may control mitochondrial respiration through post translational modification or respiratory …
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Insights into the Functional Link between MtHsp40:MtHsp70 Network and Mitochondrial Homeostasis
… of mtHsp70, with the exception of substrate binding domain-deletion mutant, did not affect mitochondrial morphology. These data suggest that the stoichiometric ratio between mtHsp40 and mtHsp70 determines mitochondrial morphology independently of apoptosis. Mitochondrial fragmentation …
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Oxygen diffusion limitations in pancreatic islet culture and immunoisolation
Data for oxygen consumption by rat islets of Langerhans in a batch microreactor were fitted using a numerical solution of the transient oxygen diffusion-reaction equation. Average best-fit values were 3.1 +/- 0.7 x 10-8 mol/cm3-s for the maximum oxygen consumption rate Vmax in aminoacid-free media …
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Investigating IL-15 Metabolic Impact and Its Mechanism of Action in Skeletal Muscle Cells
… overexpression in skeletal muscle in mice generates a very lean and active phenotype. However, there are discordant reports throughout scientific literature. The aim of the current study was to 1) characterize the metabolic effects of IL-15 in L6 myotubes to determine whether L6 is a good model …
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Bisphenol A and Obesity
… different developmental periods. Body mass, food consumption, leptin levels, and oxygen consumption rate were measured for both studies, with body composition analysis conducted only in P2. There was no change in food consumption or oxygen consumption for either Phase. Low dose male mice (P1, …
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New phosphorescence based probes and techniques for the analysis of cellular oxygen and respiration
Real time monitoring of oxygenation and respiration is on the cutting edge of bioanalysis, including studies of cell metabolism, bioenergetics, mitochondrial function and drug toxicity. This thesis presents the development and evaluation of new luminescent probes and techniques for intracellular O2 …
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The effects of furosemide on equine skeletal muscle satellite cell myogenesis and metabolism in vitro
… 1 (P<0.05). Excess furosemide decreased basal oxygen consumption rate (OCR) and increased OCR after addition of oligomycin (P<0.05). Excess furosemide did not affect myotube glycolysis rates in vitro. In conclusion, furosemide inhibits muscle differentiation and oxidative metabolism in eqSCs.
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Molecular Mechanisms Underlying Aerobic Respiration and Heme Regulation in Yeast
… yeast, heme serves as a secondary messenger of oxygen, as heme synthesis depends on the intracellular levels of oxygen. Yeast and higher eukaryotes have adapted to adverse conditions including low oxygen or hypoxia. To understand the molecular mechanisms underlying hypoxia tolerance on a …
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The role of Biophotons in cellular senescence.
… ultra-weak photons (biophotons), primarily generated through ROS production. There is increasing evidence that cells can influence each other non-chemically via biophotons. In this study, I aim to elucidate the potential impact of both intrinsic biophotonic emissions and extrinsic light exposure …
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Comparison of the Barnacle, Balanus amphitrite, in Different Environments
… Sea and San Diego Bay.</p> <p>Weight-specific oxygen consumption rate was measured for 3 hours to compare respiratory responses of both populations at 18 experimental combinations of salinity (0, 15, 30, 36, 45, and 60 %o) and temperature (15, 25, and 35 °C). Although no overall significant …
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