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Showing 1 to 3 of 3 for “"OxyR response"”.
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Secondary problems caused by the oxyr response to hydrogen peroxide stress in Escherichia coli
… enzymes. E. coli uses the transcription factor OxyR to sense and respond to H2O2 stress. When the intracellular H2O2 levels rise to 0.2 μM, OxyR is activated via the formation of a disulfide bond, and it induces the transcription of the OxyR regulon. The induced genes include those that scavenge …
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Identification and characterization of a novel class of hydrogen peroxide targets in escherichia coli
… damage by H2O2 are becoming clearer. While the OxyR response increases production of H2O2 scavenging enzymes, it also plays a role in metal homeostasis through regulation of MntH and Dps. These proteins work to increase Mn concentrations, while sequestering Fe in the stressed cell, respectively. …
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Testing oxidative-stress hypotheses generated by systems-biology assays
Role of yaaA in hydrogen peroxide stress response in Escherichia coli Hydrogen peroxide (H2O2) is commonly formed in microbial habitats by either chemical oxidation processes or host defense responses. H2O2 can penetrate cell membranes and damage key intracellular biomolecules, including DNA and …