Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Oxidized low density lipoproteins"”.
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PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, ATHEROSCLEROSIS AND EXTRACELLULAR VESICLES ¿ EXPERIMENTAL AND CLINICAL EVIDENCE
… enhanced inflammatory milieu and uptake of oxidized low-density lipoproteins, whereas the migratory capacity was reduced. When injected into zebrafish embryos, VSMCPCSK9-EVs favoured the recruitment of macrophages toward the site of injection. The results of the present study provide …
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Crosstalk between CX3CL1 and the Cytoskeleton during Vascular Inflammation
… engages and internalizes cholesterol-rich, oxidized low-density lipoproteins, leading to the accumulation of cholesterol esters within macrophages, and thus, the acceleration of foam cell formation. These findings reveal a novel function of chemokines in priming macrophages for the …
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Regulation of Clathrin Mediated Endocytosis and Its Role in Cancer Progression
… antibiotic, which inhibits the uptake of oxidized low-density lipoproteins in macrophages, as well as clathrin-mediated endocytosis (CME) in plant cell lines. However, detailed characterization of IKA had yet been performed. Therefore, we performed biochemistry and microscopy experiments …
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The Signaling Pathway of Oxysterol-Induced Apoptosis in Macrophages.
<p>Oxidized low-density lipoproteins (OxLDL) mediate many of the pathological events associated with atherosclerosis. Oxysterols, the major cytotoxic component of OxLDL, induce apoptosis in macrophages by a calcium flux mediated activation of cytosolic phospholipase A<sub>2</sub> resulting in the …
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Role of Sodium Arsenite in Atherogenesis
… study, we have shown for the first time that low and environmentally relevant concentrations of arsenic accelerate atherogenesis. The objective of this study was to elucidate the mechanisms of arsenic-induced atherosclerosis by (1) characterizing the time- and concentration-dependent effects …
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Role of Sodium Arsenite in Atherogenesis
… study, we have shown for the first time that low and environmentally relevant concentrations of arsenic accelerate atherogenesis. The objective of this study was to elucidate the mechanisms of arsenic-induced atherosclerosis by (1) characterizing the time- and concentration-dependent effects …
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Pathogenesis of experimental tuberculosis in guinea pigs
… drug N-acetylcysteine. We also established that low density lipoproteins were among the host macromolecules that are oxidized during the chronic inflammatory response typical of tuberculosis. Oxidized low density lipoproteins (OxLDL), known to be rich in cholesterol, accumulated in macrophages …