Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Oxidative stress and disease"”.
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Impact of mtDNA Signature on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression and Cardiometabolic Outcomes in Mice
Cardiometabolic diseases (CMDs) are a major global health burden, with metabolic dysfunction-associated steatotic liver disease (MASLD) emerging as both a prevalent comorbidity and an independent risk factor for adverse outcomes. While diet and lifestyle are established contributors, variation in …
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Computational modeling of the IL-4 pathway to understand principles of systemic redox regulation in cell signaling
… pathological conditions such as cardiovascular disease, cancer and rheumatoid arthritis. Despite known links between oxidative stress and disease, years of clinical studies have failed to show clear benefits of antioxidant therapy. It is now recognized that ROS such as hydrogen peroxide can act …
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Investigation and validation of mammalian telomeres as biomarkers for health and disease
… role in safeguarding chromosomal integrity and have emerged as promising biomarkers of aging, oxidative stress, and disease. However, accurately quantifying telomere length (TL) remains technically challenging, particularly in murine models whose telomeres are substantially longer and more …