Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Oxidative post-translational modifications"”.
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Functional Importance of Oxidative Post-Translational Modifications of Ryanodine Receptor in Cardiac Sarcoplasmic Reticulum Ca2+ Handling During Oxidative Stress
… has been done to specifically characterize oxidative post-translational modifications (PTMs) of RyR2 as a result of oxidative stress within the ischemic or failing myocardium. Commonly observed in many disease phenotypes, including cardiovascular disease, is the prominence of glutathione …
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Novel strategies to increase Sirtuin-1 activity in aortic aneurysm
… showed that SirT1 activity can be inhibited by oxidative stress whereas mutating oxidation-sensitive cysteines on SirT1 (3M SirT1) or overexpressing glutaredoxin-1 (Glrx), an enzyme that prevents oxidative modifications on SirT1, was able to restore SirT1 activity in liver cells. OBJECTIVES: The …