Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Oxidative Stress Markers"”.
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Oxidative stress markers in neurological diseases and disorders: electrochemical detection of hydrogen peroxide and nitric oxide
… this thesis is the detection of NO and H2O2 as oxidative/nitrosative stress markers in neurological disease and dysfunction. As such the role of oxidative/nitrosative stress in Parkinson’s disease (PD) and autism spectrum disorders (ASDs) is investigated in this thesis. The novel detection of NO …
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Effects of a Saccharomyces cerevisiae fermentation product-supplemented diet on immune response, oxidative stress markers, and skin and coat health of dogs
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-05-01
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An Evaluation of exposures to respirable particulates, environmental PM2.5, PAHs and metal compounds in Western Australia
… exposure to air pollutants and potential biomarkers of health effects. The research project was conducted in 2 separate study locations and cohorts. Study 1: An Evaluation of Children’s Exposures to Respirable Particulates, Environmental PM2.5, PAHs and Metal Compounds in The South West of …
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The cryopreservation of <i>Picea sitchensis </i>germplasm
… culture locations, but biochemical profiling of oxidative stress markers, ethylene and DNA methylation did not confirm stress or epigenetic change as the cause of these differences and physiological recalcitrance.A cryopreservation protocol, using a programmable freezer (Planar), was successfully …
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Molecular analysis of the role of mitochondria in aging and lengevity
… ROS, which damages essential macromolecules by oxidative modification and may lead to mitochondrial dysfunction. Accumulation of oxidative damage caused by ROS has been implicated as a major causal factor in the age-associated decline in tissue function and implicated in many age-associated …
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Role of oxidative stress in photoreceptor degeneration
… and represent the major cellular source of oxidative stress. ROS are capable of attacking molecules such as DNA, proteins and lipids, and of compromising either the structural and functional integrity or the survival of cells. Mitochondria also play a key role in apoptosis, the major …
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Effect of yacon flour (Smallanthus sonchifolius) consumption on body weight, body composition, intestinal permeability and metabolic changes in excess body weight adults
… effect of yacon flour consumption on metabolic markers has not been studied in excess body weight adult humans. Thus, we evaluated the effect of the consumption of yacon flour associated with an energy restricted diet on body composition, food intake, intestinal function, biochemical variables …
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Depot differences in adipose tissue metabolism and function in obese black South African women and changes in response to an exercise training intervention
… body composition, hepatic fat, inflammatory and oxidative stress markers, and insulin sensitivity (SI) in obese black SA women. This research evaluated the i) FA composition of aSAT and gSAT, and red blood cell total phospholipids (RBC-TPL) and their associations with body composition, hepatic …
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NEUROINFLAMMATION AND SEX-DEPENDENT SIGNALING WITHIN THE DORSAL MEDULLA IN A MODEL OF FETAL PROGRAMMING: EFFECTS OF ANGIOTENSIN-(1-7) SUPPLEMENTATION
… BM.This dissertation focuses on the CNS markers of oxidative stress, inflammation and signaling mechanisms that act as possible contributors to BM-induced alterations and the impact of Ang-(1-7) supplementation. We demonstrate that with antenatal BM exposure, there is an increase in …
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NAC transcription factors in sugarcane and their functional role in drought tolerance
… due to the complex, polygenic nature of abiotic stress responses, highlighting the importance of identifying single regulatory elements capable of modulating multiple stress response pathways. NAC (No apical meristem [NAM], Arabidopsis transcription activation factor [ATAF], Cup-shaped cotyledon …
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The in vitro effects of diallyl trisulfide on osteoclast formation and function in RAW 264.7 murine macrophages
… The effects of DATS on the expression of oxidative stress markers were investigated in RAW 264.7 murine macrophages through western blotting. It was shown that DATS exhibited a significant increase in the expression of the antioxidative protein, nuclear factor erythroid 2-related factor 2 …
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Role of Angiotensin II Type 2 Receptors in Oxidative Stress and Inflammation
Sodium imbalance, inflammation and oxidative stress are believed to contribute to hypertension in obesity/diabetes. The renin angiotensin system (RAS) is the major hormonal system which affects sodium balance, oxidative stress and inflammation mainly via activation of Angiotensin II- AT1 receptors. …
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Physiological and Biochemical Aspects of Methionine Isomers and Precursors in Broilers
… converting enzyme gene expression and activity, oxidative stress markers, and a potential pathway related to amino acid signaling. To achieve this goal, male Cobb-500 broilers were raised from day of hatch (d0) to d35 post-hatch and fed a diet deficient in methionine and cysteine (Met + Cys) …
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Sex differences in the associations of physical fitness, physical activity, sedentarism, and sleep behaviour with oxidative stress in older adults: The INTERMAE project
… decline leading to metabolic diseases or oxidative stress. Oxidative stress has been defined as a pathophysiological state characterised by an imbalance between the excessive production of oxidants (such as homocysteine, HCY) and the inability of the total antioxidant capacity (TAC) of the …
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Time-restricted eating on inflammation and oxidative stress in overweight, older adults
… various dietary interventions on inflammation, oxidative stress, and metabolic health. Chapter 1 presents a comprehensive review discussing the rationale for assessing inflammation and oxidative stress in the context of time-restricted eating (TRE). This review suggests the potential effects of …
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Potential cardioprotective effect of chronic, moderate consumption of reduced-alcohol wine in a rat model of pulmonary hypertension
… process of PAH remains unclear but oxidative stress is thought to contribute to arterial and ventricular dysfunction. Red wine has powerful antioxidant properties and is cardioprotective. However, side effects of alcohol may limit the use of wine as a therapeutic agent. The aim of …
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Redox regulation of vascular NO bioavailability during hypoxia: implications for oxygen transport and exercise performance
… of these tissues whilst changes in molecular biomarkers of endothelial function could provide some insight into the mechanisms driving systemic and regional O2 delivery and vascular hypoxic sensing capabilities. The first study of this thesis examined the impact of acute hypoxia (FIO2 = 0.12) on …
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The effects of hydration status on markers of oxidative and cellular stress during prolonged exercise in hyperthermic environments
… between hyperthermia, dehydration and oxidative stress have been thoroughly studied separately within the literature both in vitro and in vivo. However, no in vivo attempts have been made to manipulate the hydration status of individuals to investigate the resulting changes in oxidative …
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Mechanisms of insulin resistance and β - cell failure in type 2 diabetes. Effective diet against o minous octet
Úvod a cíle: Dietní intervence je pilířem léčby diabetu 2. typu (T2D). Vegetariánská strava je zajímavou alternativou. Cíle naší studie byly následující: 1. Porovnat účinky vegetariánské a konvenční diabetické diety se srovnatelnou kalorickou restrikcí na inzulínovou rezistenci, objem viscerálního …