Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"Oxidative Capacity"”.
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Effect of Iron on the Oxidative Capacity of Carbonaceous Nanoparticles
… of reactive oxygen species (ROS) that lead to oxidative stress, significant gaps exist in the understanding of the detailed chemistry of these detrimental effects. Trace metals and carbonaceous material of the nanometer-sized particles contained in PM<sub>2.5 </sub>have been implicated as key …
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Mitochondrial mRNA Translation is Required for Maintenance of Oxidative Capacity
<p>Oxidative metabolism is required to produce adequate energy to sustain human life. A primary example of deteriorating oxidative capacity is seen in the cardiac musculature during chronic heart failure. This suggests that by improving oxidative potential, chronic heart disease could be mitigated …
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Determination of the Oxidative Capacity of Soot Toward GSH and Characterization of Soot Physicochemical Properties
… (GSH), was optimized for use as an indicator of oxidative stress to shed light on relevant particle characteristics. This was accomplished via fluorescent spectroscopy for GSH determination by way of reaction with <em>o-</em>phthalaldehyde (OPA), a fluorescent marker. Physicochemical properties …
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Uncertainties in estimates of the oxidative capacity of the urban atmosphere : a modeling and measurement approach
Mobile emissions represent a significant fraction of the total anthropogenic emissions burden in megacities and have a deleterious effect on air quality at local and regional scales. Due to the significant sources of uncertainties involved during the estimation of mobile emissions, an adequate …
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Long term trends of halogenated trace gases, hydrocarbons, alkyl nitrates and of the oxidative capacity of the atmosphere
Atmospheric trends of a series of ozone depleting substances (halons) and greenhouse gases (PFCs, SF5CF3, HFC-227ea) are reported using measurements from Cape Grim, Tasmania. A two-dimensional global atmospheric chemistry transport model is used to derive global annual emission histories of these …
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The Effect of Resveratrol On Skeletal Muscle Function, Muscle Pathology, and Oxidative Capacity In the Mdx Mouse Model of Duchenne Muscular Dystrophy
… the muscle damage are inflammation and oxidative stress. ATP production, particularly oxidative metabolism, is also compromised with this disease further reducing muscle function. Resveratrol reduces inflammation, oxidative stress, enhances oxidative metabolism, and activates the …
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AMP-activated protein kinase and muscle metabolism
… and creatine would decrease ATP buffering capacity, resulting in earlier termination of glycolysis and pH decline. Dietary supplementation with the creatine analogue, β-GPA, decreased muscle total creatine but negatively affected performance. Another experiment was conducted using control …
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The Effect of Post-Injury Exercise Training on Skeletal Muscle Mitochondria
… switch phenotypes. Mitochondrial content and oxidative capacity are secondary indicators of fibre phenotype and may be similarly affected by external stimuli during exercise and regeneration due their overlapping regulatory pathways. Previous research observed an increase in fast twitch …
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Blood Lactate Predicts Resting Energy Expenditure in Non-Obese Caucasian Females
… High basal plasma lactate levels, reduced oxidative capacity, and insulin resistance are co-morbidities with these metabolic disorders. However, it is unknown if those co-morbid traits are also displayed in the non-obese who may be predisposed to obesity. A higher plasma lactate …
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Dietary and exercise manipulation of skeletal muscle function in older humans
… muscle (‘sarcopenia’), a decrease in muscle oxidative capacity and a reduction in muscle strength. Research has shown that it is possible to arrest, or even reverse, the changes in muscle mass and oxidative capacity that occur with age. Two of the most successful strategies identified to date …
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The Role of Angiotensin II in Skeletal Muscle Metabolism
… using 14C-glucose. In addition,mitochondrial oxidative capacity was measured using an XF 24 Flux Analyzer (Seahorse Bioscience) and reactive oxygen species measured using confocal microscopy. The clinical study involving the drug Benicar ® investigated the metabolic effects of blocking …
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Exogenous Mitochondrial Transfer and IL-6: Modulating Adipocyte Metabolism in Obesity-associated Dysregulation
… potential for improving energy expenditure and oxidative capacity within adipocytes. Surprisingly, mitochondrial therapy resulted in increased IL-6 levels, contradicting earlier studies showing IL-6 reduction in other injury models. The role of IL-6 in adipose tissue metabolism and obesity has …
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Effects of Resistance Training on aged Skeletal Muscle and Mitochondrial Function
… in a lower resting metabolic rate, reduced lipid oxidative capacity, increased adiposity, and insulin resistance. The rising number of individuals aged 65+ will increase demands on health care and health care costs, possibly leading to inadequate public resources and less care for the aged. This …
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Skeletal muscle mitochondrial capacity and metabolism in lung transplant patients and resistance trained subjects
… effects of resistance training on mitochondrial oxidative capacity in skeletal muscle.
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Regulation of Metabolic Processes by Micrornas and Class I Histone Deacetylases
… mitochondrial fatty acid metabolism and elevated oxidative capacity of insulin-target tissues. Taken together, our findings reveal that miR-378 and miR-378* function as integral components of the regulatory circuit formed by PGC-1beta and nuclear hormone receptors to control the overall oxidative …
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Inactivity and overfeeding related changes in skeletal muscle composition and metabolism in captive felids - are they at risk of developing metabolic syndrome?
… fibre type composition, fibre size, and maximum oxidative (citrate synthase (CS), 3-hydroxyacyl CoA dehydrogenase (3HAD) and glycolytic (phosphofructokinase (PFK) and lactate dehydrogenase (LDH) enzyme capacities. The type IIA fibres were the predominant fibre type in both the wild (48%) and …
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Energy metabolism in skeletal muscle: mechanistic insights into mitochondrial function and growth
… mutation (AMPKγ3R200Q) that results in greater oxidative capacity in a habitually glycolytic skeletal muscle. We discovered BAA supplementation stimulates beta-1 adrenergic receptor gene expression and impacts mitochondrial respiration. Interestingly, BAA feeding had more effect on control pig …
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Skeletal muscle composition in various breeds of domestic dogs: (A comparative study)
… analysed for fibre type composition, fibre size, oxidative and glycolytic metabolic capacity (citrate synthase (CS), 3-hydroxyacetyl co A dehydrogenase (3-HAD), creatine kinase (CK) and lactate dehydrogenase (LDH) enzyme activities). There was no significant difference between the TB and VL in any …
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The Impact of Interval Intensity in Overweight Young Men
… peak work rate on a cycle ergometer. Aerobic capacity measurements, time to completion trials, muscle biopsies, and fasted blood samples were all performed pre and post training. Analyses of aerobic capacity and exercise performance demonstrate greater improvements made in the 100% compared to …
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