Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Oxford Nanopore Sequencing"”.
-
A sequencing-based analyisis of epigenetic modifications of the mitochondrial genome
… has been studied using whole genome bisulfite sequencing (WGBS), but recent evidence has uncovered major technical issues, which introduce a potential bias during methylation quantification. In this study, we first validate the technical concerns with WGBS using publicly available datasets. …
-
Analysis of DNA methylation in canine osteosarcoma using next generation sequencing technology
… cell line (OSCA-29) was sequenced using Nanopore sequencing. Oxford Nanopore sequencing is a sequencing method that measures the variation in ionic current through a biological nanopore as a single-stranded nucleic acid is ratcheted through. These signals can then be used to determine DNA …
-
Expanding Genetic and Genomic Resources for Sex Separation and Mosquito Control Strategies
… of classical genetics, recent advances in sequencing and genome-editing technologies, and the use of modern forward genetics approaches. Chapter 2 of this dissertation explores the use of the Oxford Nanopore Sequencing Technology for the first time in mosquitoes. This new technology …
-
Investigating the effects of genetic variation on heterochromatic crossover events in Arabidopsis thaliana
Crossover events result in the reciprocal exchange of genetic material between homologous chromosomes during meiosis. Numerous genetic and environmental factors have been shown to influence the meiotic recombination landscape in many different species. My thesis uses the model plant *Arabidopsis …