Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Overnutrition"”.
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Effect of pre-natal overnutrition on renal development in the rat
Thesis (M.S.)--Michigan State University. Dept. of Food Science and Human Nutrition, 1976
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Bioenergetic and Metabolic Signatures of Maternal Overnutrition in the Offspring Heart
… metabolic dyshomeostasis, the impact of maternal overnutrition on hepatic mitochondrial respiratory function and metabolism was also assessed. Maternal obesity exposure lowered mitochondrial ETS capacity in young adult offspring. Whilst hepatic triglyceride content was unchanged by maternal diet, …
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The impact of maternal overnutrition during the periconceptional period on the development of postnatal obesity in the sheep.
… diet (70% MER). To determine the effect of overnutrition in the periconceptional period only, single embryos were then transferred to recipient ewes which were maintained on a control diet (100% MER) for the remainder of pregnancy. All ewes were allowed to give birth naturally. At 4 months …
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Broad Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β-cell Metabolism in the Absence of Dietary Overnutrition
<p>SIRT3 is an NAD+-dependent mitochondrial protein deacetylase purported to influence cellular and systemic metabolism through modulation of the mitochondrial acetylproteome. Fuel-stimulated insulin secretion from pancreatic islets involves mitochondrial metabolism and might be susceptible to …
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The double burden of malnutrition in South Africa: risk factors for undernutrition and overnutrition and the development of a novel mid-upper arm circumference (MUAC) screening tool in children
… to validate the new cut-off values for under and overnutrition. A validation dataset of 247 infants and young children from the Eastern Cape, South Africa. It was found that the new MUAC values performed well for identifying acute malnutrition (100% sensitivity, 99.1% specificity, PPV=0.25, …
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Targeting the intestinal stem cell niche through energy and metabolism signaling, for colorectal cancer chemoprevention using aspirin and metformin
… metabolism. Growing evidence indicates that overnutrition increases ‘stemness’: the ability of intestinal stem cells to self-renew or differentiate. The mechanistic target of rapamycin (mTOR) pathway, a central metabolic regulator, is elevated in CRC and modulates stem cell response to …
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Metabolic phenotypes of infants with normal birth weight, small-for-gestational-age, or after maternal gestational diabetes mellitus
Numerous studies have associated both under- and overnutrition during early life with long-term metabolic outcomes. Those conditions are typically represented by two groups of infants in animal and human studies: infants born small-for-gestational-age (SGA; reflecting intrauterine undernutrition) …
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The impact of suboptimal maternal diet on fetal heart development: Identifying targets for intervention
… how exposure to a suboptimal diet (under- and overnutrition) at different timings, severities, and durations impacts growth, hormonal, metabolic, and contractile profiles within the fetal heart. Across studies, it was highlighted that high-risk cardiac phenotypes are present even with normal …
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NUTRITIONAL STATUS OF SCHOOLING CHILDREN IN TANZANIA AND UGANDA: RESEARCH AND ACTION
… With its different faces – undernutrition and overnutrition – it is the result of several determinants, such as the lack/surplus of adequate food, life-style, mother’s low education, socio-economic situation. For this reason, any research on this issue should be tackled with a wide approach. …
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TEMPOL and Insulin Resistance: A study of the underlying mechanisms behind changes in glucose metabolism, lipid accumulation and cellular stress
… factors are major contributors to obesity. Overnutrition-induced obesity drives oxidative stress and inflammation, leading to insulin resistance. There are currently no successful treatments to treat insulin resistance or its downstream clinical sequelae. It was hypothesized that TEMPOL, a …
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Metabolic Mechanisms of Nutritionally Regulated Hormone Signaling on T Helper Cell Function
… and tissues throughout the body. In the case of overnutrition or obesity, levels of leptin, insulin, and insulin like growth factor 1 (IGF-1) are increased, whereas they are decreased in the setting of undernutrition. Either undernutrition or overnutrition results in a dysregulated immune …
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Prevalence and determinants of obesity among adolescents in Vhembe district Municipality, Limpopo Province
… a double burden and trend of undernutrition and overnutrition.
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Characterizing the role of dietary fat in the development and progression of liver dysfunction
… fatty liver disease in popular murine models of overnutrition, as well as a novel hen model. Major findings from this work showed that (1) exposure to a high-fat diet during early adulthood preserves metabolic homeostasis, modifies liver morphology, and protects against obesity-related disease, …
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Describing The Nutritional Outcomes Following Paediatric Liver Transplantation At A Tertiary Hospital In South Africa
… seems prudent to prevent the development of overnutrition and associated metabolic complications.
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RELATIONSHIP BETWEEN ILLNESS AND ADIPOSITY IN CHILDHOOD
… now shifted from undernutrition to the impact of overnutrition on childhood illness. Especially in children, studies on this association are sparse. The aim of this secondary data analysis research project was to investigate the relationship between illness in the first two years of life and …
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Putting Food onto the Urban Agenda: How the City of Cape Town can increase access to sustainable and healthy diets through urban food governance
… with hunger and undernutrition but also with overnutrition. Due to structural barriers in cities limiting access to healthy food, the urban poor are disproportionally affected by nutrition-related diseases. In addition to the impacts on human health, modern dietary patterns and food production …
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Identification and Delineation of Neuronal Pathways Underlying Hypophagia
… disorders manifest in two extreme directions: overnutrition, which can lead to obesity, and malnutrition, which can result in underweight or even starvation. Both extremes compromise the quality of life. According to the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) standard, …
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Dissecting NAMPT Signaling Pathways in Beige Adipocyte Development, Impairment and Maintenance
… plasticity and undergo “whitening” during aging, overnutrition, and thermoneutrality. The NAD(^+) biosynthetic enzyme nicotinamide phosphoribosyltransferase (NAMPT) regulates cellular stress responses and immune–metabolic crosstalk, yet its roles in thermogenic adipocyte development, maintenance, …
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Low intake of fruits and vegetables in Thailand : magnitude, disease burden and urban influence
… those health problems of both under- and overnutrition. This study aimed to demonstrate the current situation of low intake of fruits and vegetables in Thailand, as well as its potential impact that increased fruit and vegetable intake could help save life lost from cardiovascular diseases …
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Double burden of malnutrition among women in South Africa: evidence from the demographic health survey
… defined as the coexistence of undernutrition and overnutrition within the same population, community, or individual. The phenomenon can manifest at individual, household, or population levels and has significant public health implications. Methodology: The thesis includes a comprehensive …
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