Global ETD Search
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Showing 1 to 5 of 5 for “"Outer membrane vesicle"”.
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Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
… O86a:K61 secretes the protease OmpT as part of outer membrane vesicles (OMVs), which inactivates coagulation Factor V and in so doing, induces a hemorrhagic state. To further characterize the effect of OmpT on the coagulation, this study has employed a genetic approach using wild type, an OmpT …
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Outer Membrane Vesicle Production in Escherichia coli Relieves Envelope Stress and is Modulated by Changes in Peptidoglycan
<p>Bacterial outer membrane vesicles (OMVs) are spherical buds of the outer membrane (OM) containing periplasmic lumenal components. OMVs have been demonstrated to play a critical part in the transmission of virulence factors, immunologically active compounds, and bacterial survival, however …
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Inhibition of extracellular vesicle release enhances cancer chemotherapy and inhibition of outer membrane vesicle release sensitises bacteria to antibiotic and bacteriophage therapy
Extracellular vesicle (EV) release from tumour cells plays an important role in cancer drug resistance. It is essential that chemotherapeutic drugs are retained within target cells for increased efficacy in inducing apoptosis and as microvesiculation influences drug retention, this study has …
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Characterization of a secreted escherichia coli 086a:K61 protease that inactivates human coagulation FV
Background: Escherichia coli (E.coli) O86a:K61 belongs to the Enteropathogenic E. coli (EPEC) group of pathogens. Acute gastroenteritis affects 2-4 billion people annually and EPEC is associated with 10-40% of hospitalized diarrhea cases globally. Coagulation Factor (F) V circulates as an inactive …
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Investigations of enterotoxigenic E. Coli (ETEC) intestinal colonization in neonatal mice and human shedding of panchol, a new live attenuated oral cholera vaccine
BACKGROUND: Vibrio cholerae and Enterotoxigenic E. Coli (ETEC) are enteropathogens that are global causes of cholera and traveler’s diarrhea which are responsible for millions of diarrhea cases every year. ETEC and cholera are primarily found in Sub-Saharan Africa and Asia, particularly in nations …