Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Outer membrane permeability"”.
-
ACCELERATING WHOLE-CELL BIOCATALYSIS BY ENHANCING OUTER MEMBRANE PERMEABILITY
… cell envelope often represents a formidable permeability barrier. As a result, reactions catalyzed by whole-cells are reportedly orders of magnitude slower than those of by their free enzyme counterparts. The present research addresses this critical issue by using membrane engineering …
-
Visualizing the attack of bacteria by the antimicrobial peptide human defensin 5
… studies we propose that HD5ox overcomes the outer membrane permeability barrier and permeabilizes the inner membrane of Gram-negative bacteria, and it may interact with the cellular targets and interfere with the processes such as cell division. We extended these morphological studies of HD5 …
-
Improving antibiotic activity by manipulating bacterial reactive oxygen species metabolism
… primarily because these bacteria possess an outer membrane that prevents many antibiotics from accessing their primary cellular targets. While the discovery of novel antibiotics could help to address these issues, alternative strategies, such as improving the activity of preexisting …
-
BIOPHYSICAL STUDIES OF THE MECHANISM OF CERAMIDE CHANNEL DESTABLIZATION BY BCL-XL IN APOPTOSIS AND THE USE OF RECTIFICATION TO PROBE THE STRUCTURE AND DYNAMICS OF A NOVEL ESCHERICHIA COLI CHANNEL
… a novel type of channel in the mitochondrial outer membrane and these channels are involved the release of intermembrane space proteins from mitochondria, a decision-making step in the apoptotic process. An antiapoptotic protein, Bcl-xL, regulates the apoptotic process and inhibits the …
-
Evaluation of the Interplay between β-Lactamase Expression and Porin Loss in β-Lactam Susceptibility Profiles in Escherichia coli
… of β-lactamase production, alterations in outer membrane permeability, and regulatory mechanisms influencing gene expression. In particular, the major embedded outer membrane porins OmpC and OmpF play a critical role in modulating antibiotic influx and can significantly impact β-lactam …
-
Cargo delivery into gram-negative bacteria via enterobactin uptake machinery
… deliver antibacterial cargo across the outer membrane permeability barrier of Gram-negative pathogens that utilize enterobactin for iron acquisition. Chapter 4. Stability Evaluation of Acyloxymethyl/Acyloxyethyl Ester Linker for the Design of Enterobactin-fluoroquinolone Conjugates …
-
Role of Bacterial Lipocalin Proteins in Antimicrobial Resistance
… which stimulates the oxidative stress and membrane lipid peroxidation. BcnA lipocalin, and associated proteins BcoA cytochrome and BarA reductase are involved in membrane peroxidation stress response to antibiotics and other forms of oxidative stress. I report that bcnA, bcoA and barA …