Global ETD Search
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Showing 1 to 4 of 4 for “"OtsA"”.
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Targeting Trehalose and Methylglucose Lipopolysaccharide Biosynthetic Pathways in M. tuberculosis - Structural and Functional Characterisation, and Early-Stage Drug Discovery of OtsA and Rv3030
… two pathways for synthesis of trehalose, the OtsA-OtsB pathway and the TreY-TreZ pathway. Multiple biosynthetic pathways underline the critical role that trehalose plays in the bacteria. OtsA-OtsB is the dominant pathway, required for bacterial growth in laboratory culture and for virulence in …
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Structure-guided insights into the functions of CHIKV nsP2
… interaktsioone nsP2 valgu ja CHIKV genoomi 3' otsa vahel. Nende interaktsioonide takistamine muudab viiruse paljunemisvõimetuks. 2: Paindlik domeenide vaheline regioon, mis ühendab nsP2 valgu N-otsa poolset helikaasi ja C-otsa poolset proteaasi piirkondi, on CHIKV replikatsiooni jaoks samuti …
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Glucan metabolism in mycobacterium and streptomyces
… this study, another mutant from S. venezuelae ΔotsA was also investigated, which was hypothesised to be feeding the substrate trehalose into the GlgE pathway from glucose. However, under normal laboratory growth conditions, no phenotype was observed and the strain was able to accrue α-glucan. …
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Identification of strains of Rhizobium leguminosarum
… These were trehalose-6-phosphate synthase (otsA), trehalose-6phosphate phosphatase (otsB), maltooligosyltrehalose synthase (treY), maltooligosyltrehalose trehalohydrolase (treZ) and trehalose synthase (treS). Only otsB produced readable DNA sequences suitable for analysis. When the DNA …