Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"Other Neuroscience and Neurobiology"”.
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Proliferation, Migration, and Survival of Cells in the Telencephalon of the Ball Python, Python regius
… telencephalon-wide neurogenesis in adulthood, and no studies have performed these investigations in snakes. Quantifying neurogenesis in the adult snake is essential to understanding class-wide adult neurogenesis and providing insight into the evolution of this trait. The thymidine analog …
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Medial Prefrontal Cortex fNIRS Activity while Viewing Nature and Urban Scenes: The Search for Neurological Evidence of Nature's Transcendent Self-Diminishment Effect
… less attention to oneself. To better understand the neural processes behind this, this study used functional near-infrared spectroscopy (fNIRS) to measure activity in the medial prefrontal cortex (mPFC) which is related to the self-concept. Participants were shown 12 images divided into four …
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Effects of Resting State On Perceptual Learning
… general mechanism by which neural networks learn and store sensory information. However, whether reactivation occurs in areas relevant for perceptual learning is unknown.</p> <p>To investigate how sleep affects perceptual learning at the level of single neurons and networks, an experimental …
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Improving dopamine monitoring with NCAM and the effects of intranasal oxytocin on dopamine signaling in the rat brain
… is a neurohormone highly involved in learning and memory. Oxytocin (OXT), another neurohormone, has also been implicated in learning and memory. Fast-scan cyclic voltammetry (FSCV) is a method used for the real-time examination of DA neurotransmission in the brain. Implanting FSCV electrodes is …
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Non-Photic Mechanisms of Entrainment In Bmal1 Deficient Conditions
… clock is imperative to our daily biological and mental well-being. Large epidemiological studies have shown that disruptions of our circadian rhythms can lead to poor mental health, metabolic diseases, and various types of cancer. Various external cues that have become a part of the modern …
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Discovery and Elucidation of The Fgfr3-Tacc3 Recurrent Fusion In Glioblastoma
… where two previously separate genes rearrange and fuse together, forming a hybrid gene. The first fusions were reported in leukemias; however, with the advent of more powerful sequencing technologies, fusions have recently been reported in several solid tumors. Using next-generation deep …
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Ube4B Levels Determine The Efficacy of Egfr and Stat5 Inhibitors In Treatment Resistant Neuroblastoma
… EGFR signaling, uncontrolled proliferation, and may provide a mechanism for chemotherapy resistance. UBE4B, an E3/E4 ubiquitin ligase, ubiquitinates the EGFR and promotes its lysosomal degradation ultimately attenuating EGFR signaling. Interestingly, the UBE4B gene lies in a chromosomal …
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A Longitudinal Examination of Depressive Symptomology in Concussed and Injured, Non-concussed Division I Student-athletes
… I collegiate athletics.<br />PATIENTS OR OTHER PARTICIPANTS: Concussed, injured/non-concussed, and healthy Division I collegiate student-athletes (age 18-22) competing in football, wrestling, men’s basketball, and women’s basketball.<br />INTERVENTION(S): Participants completed the Center …
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Direct Inputs to off Α and G9 Ganglion Cells From Aii Amacrine Cells In Rabbit Retina
… ganglion cell types in the rabbit retina, OFF α and G9, were identified by a combination of morphological criteria such as dendritic field size, dye coupling, mosaic properties and stratification depth. The AII amacrine cells (AIIs) were labeled with an antibody against calretinin and glycine …
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Modeling Therapeutic Strategies for Diabetic Pathologies
<p>No abstract available</p>
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You Hurt My Feelings: Autonomic and Behavioral Responses to Social Exclusion and the Moderating Effect of Psychopathic Traits
<p>Humans have a fundamental need to form and maintain social connections, and thus experiencing social exclusion is extremely distressing as it threatens this basic human need. Individuals who are socially excluded often respond aggressively, not only towards their ostracizers but also towards …
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Behavioral Responses to Methylphenidate: Correlations With Neuronal Activity In The Caudate Nucleus
<p>Methylphenidate is currently a drug of abuse and readily prescribed to both adolescents and adults. Chronic methylphenidate (MPH) exposure results in an increase in DA in the motive circuit, including the caudate nucleus (CN), similar to other drugs of abuse. This study focuses on research aimed …
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Ultrastructural correlates of axons and synapses belonging to different circuits in ferret primary visual cortex
… reconstruction of electron microscopy images, and subsequent ultrastructural analysis of axonal populations provides us with a better understanding of the connectivity of the neural circuits. By quantifying ultrastructural differences in axonal processes such as synaptic densities, types of …
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The Role of Vps54 in Drosophila melanogaster Neuronal Development and Age Progressive Neurodegeneration
… in Vps54. This mutation causes neurodegeneration and is subsequently used as a model for human motor neuron disease. Presently, it is unclear how disruption of GARP complex function leads to motor neuron degeneration. To better understand the role of Vps54 in motor neuron development, function, …
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The Extracellular Domains of the AMPA, Kainate, and Orphan Delta Receptor Regulate Channel Gating in Distinct Ways
<p>The ionotropic glutamate receptors are ligand-gated cationic channels essential for neuroplasticity and neurological functions such as learning, memory, behavior, cognition, and motor coordination. Mutations in these channels are linked to various disorders including autism, ataxia, and …
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Mechanisms of Astrocyte Contribution to Bortezomib-Induced Peripheral Neuropathy
… used in the treatment of multiple myeloma and other non-solid malignancies, alone or in combination with other chemotherapy drugs. Like other chemotherapeutic agents, bortezomib treatment is frequently accompanied by chemotherapy-induced peripheral neuropathy (CIPN) that may be …
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An EEG Study on Loneliness and Recognition Memory
… but the relationship between loneliness and recognition memory (i.e., recollection and familiarity) has not been thoroughly examined. The current study hypothesized that more lonely individuals would have lower recognition memory performance, specifically recollection, with smaller ERP …
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Using Fundamental Properties of Light to Investigate Photonic Effects in Condensed Matter and Biological Tissues
… characteristics such as polarization, wavelength and coherence. The interaction of light and matter, whether in a semiconductor or in a biological sample, can reveal important information about the internal properties of a system. My thesis focuses on two areas: photocarriers in gallium arsenide …
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Sustained Adrenergic Signaling Promotes Cervical Cancer Progression
<p>Background: Chronic stress and sustained adrenergic signaling are known to promote tumor progression. The underlying mechanisms behind this process are not well understood. We examined the effects of sustained adrenergic signaling on cervical cancer progression through increased expression of …
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