Global ETD Search
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Showing 1 to 3 of 3 for “"Other Basic Medicine"”.
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Complement in Disease - Extracellular Proteins as Complement Regulators
… attack. This might interfere with immunotherapies that aim at directing complement responses towards multiple myeloma cells. Taken together, several novel interactions between endogenous ligands and complement have been found, which might regulate the progression of different disease …
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Complement evasion strategies of human pathogens - the evolutionary arms race
… of periodontitis. Further, we showed that another important periopathogen, Prevotella intermedia, acquires resistance towards complement by binding complement inhibitor found in human serum, factor I, and its two major cofactors C4b-binding protein (C4BP) and Factor H. This mechanism …
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Genetic, molecular and functional analyses of factor I - an inhibitor of the complement system
… mutations, deletions or autoantibodies against other complement proteins. In the other two studies we detected five mutants that showed impaired function for degrading C3b present on cell surfaces. Only two of these five mutants also had reduced activity in the cleavage of C3b and C4b in the …