Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Osteoporotic fracture"”.
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Economics of Osteoporotic Fracture Prevention and Care
My thesis addresses the economics of osteoporotic fractures, a concern brought to light by aging populations and cost pressures on health systems. Central to my PhD is the utilization of health economic research to identify interventions that offer the best value for money, particularly in the …
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Improving patient outcomes after a suspected osteoporotic fracture: Exploring New Zealand orthopaedic nurses' knowledge of osteoporosis and their perception of their role in the prevention of osteoporosis and in the diagnosis, treatment, and education of patients presenting with a suspected osteoporotic fracture
… treatment of patients who have had a suspected osteoporotic fracture. A literature review revealed internationally that, nurses’ knowledge of osteoporosis is at the same level than that of lay people. No literature regarding the knowledge of osteoporosis nurses in New Zealand have, has been …
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Fracture healing in osteopenic bone and the influence of simvastatin
… recent improvements in the ability to prevent osteoporotic fracture a vast number of mainly elderly patients continue to sustain fractures resulting in significant morbidity and a huge demand on health care services. Current knowledge of the process of fracture healing in osteoporotic bone is …
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Using finite element models under multiple loading conditions to improve the association between radius and tibia microarchitecture and prevalent osteoporotic vertebral fracture
… between individuals with a prevalent vertebral fracture and healthy controls. As fracture is a result of mechanical failure, FE models of these sites in physiologically relevant loading conditions (compression, torsion, bending) may reveal insight into fracture pathogenesis uncaptured by …
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Using quantitative ultrasound for epidemiological research : associations with risk factors for low bone mineral density in South African premenopausal women
… has shown to be a reliable predictor of osteoporotic fracture. This study aims to evaluate the use of QUS in epidemiological studies in South African settings. To this end, this report determines whether characteristics associated with QUS measures of bone strength in a large sample of …
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Genetics Analysis of Bone Size Variation of Hip, Spine and Wrist in Human Pedigrees
Bone size is an important determinant of osteoporotic fracture. However, the importance of genetic factors in determining bone size variation is unknown. My purposes here are three-folded. 1) Estimate the heritability (h2) of bone size by adjusting for several significant factors such as age, sex …
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The clinical characteristics, complications and treatment outcomes of patients with osteoporosis at Groote Schuur Hospital
… problem worldwide as the population ages. An osteoporotic fracture is associated with a high rate of morbidity and mortality. Data on the prevalence, risk factors and outcome of osteoporotic fractures in South Africa remains sparse. Method: A retrospective audit was undertaken in all patients …
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Economic evaluation of three preventive drug therapies for osteoporotic fractures among women at different risk levels
… (CE) of three drug therapies for preventing osteoporotic fractures in postmenopausal women from a state Medicaid Program perspective using the estimated risk distribution in the study population. The three therapies are: hormone replacement therapy (HRT), alendronate, and raloxifene. Methods. …
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MRI Quantification of Cortical Bone Microstructure and Material Composition with Ultrashort Echo Time Sequences
… bone imaging biomarkers are associated with osteoporotic fracture independent of age, sex, height, weight, or mineral density. Recent advances in solid-state 1H and 31P MRI have demonstrated feasibility of ionizing-radiation-free quantification of cortical bone microstructure, organic matrix …
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Role of the RUNX2 rs59983488 variant in bone mass determination and fracture risk in Malta
… leading to an increased fragility fracture risk. The Runt-related Transcription Factor 2 (RUNX2) protein encoded by the RUNX2 gene is involved in the maturation and differentiation of osteoblasts and chondrocytes that are, crucial for endochondral bone formation. The RUNX2 …
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Peak Bone Mass, Lifestyle Factors and Birth Weight: A study of 25-year old women
… until the ultimate outcome, the fragility fracture occurs. Regulation of bone mass is controlled by genetic, environmental and nutritional influences. Peak bone mass, defined as the maximum bone mass accrued, is usually reached by the third decade of life and is an important determinant of …