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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"Osteonecrosis"”.
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Osteonecrosis. Prognosis and Prevention of the Consequences of Osteonecrosis
Abstract Background Osteonecrosis (ON) is defined by the in situ death of bone cells, osteocytes, hematopoietic and fatty marrow precursor cells. Events and risk factors known to be associated with ON are femoral neck fracture, hip dislocation, slipped capital femoral epiphysis in children, humeral …
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Bisphosphonate-related osteonecrosis of the jaw
… complication termed “Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)”. To date, the true incidence, etiology, and risk factors that contribute to BRONJ pathogenesis are unknown. In this dissertation, we assessed the frequency, etiology and risk factors that contribute to BRONJ …
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Osteonecrosis: Cape wine as an aetiological agent
Ischaemic necrosis of bone, particularly of the femoral head appears to be an increasing cause of musculoskeletal disability in relatively young people (Hungerford 1981). The disease is usually progressive, resulting in the destruction of major weight-bearing joints requiring arthrodesis or …
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Osteonecrosis of the jaw in association to bisphosphonates
… Paget's disease and other bone malignancies. Osteonecrosis of the jaw (ONJ) has been recently recognized as a possible complication of the use of bisphosphonate therapy. This study includes a review of the literature on the mechanism of action of bisphosphonate and its potential association to …
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Ex-Vivo Injection of Biomaterial Biologics for Treatment of Osteonecrosis
BACKGROUND: A loss of blood flow to bone produces osteonecrosis, characterized by cell necrosis and tissue destruction. This necrotic microenvironment induces chronic inflammation, poor bone regeneration, joint deformity, osteoarthritis, and potentially a total joint replacement. One potential …
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Medication-Related osteonecrosis of the jaw in women with breast cancer. a literature review /
… carries risks, including adverse events such as osteonecrosis of the jaw (ONJ). Due to the impact of these drugs on the jaw bone, this condition is now known as Medication-related osteonecrosis of the jaw (MRONJ).This literature aims to provide a comprehensive investigation into MRONJ in the …
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Adverse Effects of Asparaginase in Pediatric Patients with Acute Lymphoblastic Leukemia
… by adverse effects, such as hypersensitivity, osteonecrosis and pancreatitis.</p> <p>Hypersensitivity to asparaginase typically requires discontinuation of current formulation and substitution with other formulations, but the differential diagnosis can be challenging, and the diagnostic utility …
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Treatment of Medication-Induced Osteonecrosis of the Jaws, Using Platelet-Rich Fibrin PRF // Лечение на медикаментозно-индуцирана остеонекроза на челюстите с приложение на богат на тромбоцити фибрин PRF
Medication-induced osteonecrosis of the jaws (MRONJ) in an area of exposed bone, which does not heal in a period of more than eight weeks and affects patients underdoing medication therapy. These are mostly patients diagnosed with cancer and on intravenous treatment. The impact of the disease …
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약제관련 악골괴사에 관한 임상적 연구
약제관련 악골괴사 (Medication-related osteonecrosis of the jaw, MRONJ)는 골 흡수 억제제나 혈관 형성 억제제를 현재 투여 받고 있거나 투여 받았던 기왕력이 있고, 두경부에 방사선 치료를 받은 적이 없는 환자에서 8주 이상 지속되는 악골의 노출로 정의되는 질병이다. 지금까지 악골괴사와 관련된 약물로 비스포스포네이트 (Bisphosphonate)가 주를 이루어 왔으나 최근 다른 골 흡수 억제제나 혈관 형성 억제제에 의한 악골괴사 증례의 보고가 증가하고 있다. 본 연구는 경기 남부권의 3차 …
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Integrated Multimodal Genomic Analyses Reveal Novel Mechanisms of Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
… of glucocorticoid induced toxicities, such as osteonecrosis, can significantly affect patient quality of life and are associated with high dose glucocorticoid treatment in pediatric patients. Both endogenous and exogenous glucocorticoids exert their mechanism of action through various …
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Radiotherapy for head and neck paragangliomas: A 10 year retrospective review 2005-2014 at Groote Schuur Hospital and UCT Private academic hospital
… One patient in the radiosurgery group developed osteonecrosis of the temporal bone at 5 year follow up. Conclusion. Radiosurgery and radiotherapy are efficacious in achieving tumour control with minimal morbidity. Tumour control rates in the study are similar to control rates in literature. …
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Characterization of Bone Pathology in Sickle Cell Disease and Therapeutic Strategies
… the onset and progression of sickle osteonecrosis, gender differences in sickle pathology, the influence of chronic oxidative stress on bone cell physiology, as well as the benefits of antioxidant therapies on sickle bone quality. This thesis will serve as the foundation for the …
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Effect of Zoledronic Acid on Maxillary Alveolar Bone Coverage in Rice Rats With and Without Dental Trauma
… a condition known as bisphosphonate related osteonecrosis of the jaw (BRONJ) has emerged over the last ten years. While this condition has been linked to multiple risk factors, high dose BP usage and trauma in the oral cavity have been shown to be the primary events that precede the …
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Atención farmacéutica en pacientes con osteoporosis: tratamiento con Bifosfonatos.
… para así evitar complicaciones como la osteonecrosis maxilar. El 89% no era consciente de los riesgos asociados a una intervención de cirugía bucal estando en tratamiento con bifosfonatos. Se pudo confirmar que el alendronato fue el bifosfonato más prescrito en la muestra poblacional. …
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An assessment of the oral health status and dental treatment needs of oncology patients receiving bone modifying agents
… planning, poor knowledge of medication-related osteonecrosis of the jaw (MRONJ) amongst general medical practitioners (GMPs), and management of these patients in the emergency setting. Patients expressed concerns about the additional burden of dental care, their lack of knowledge of MRONJ prior …
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CHILDREN’S HIPS: INNOVATION IN THE DIAGNOSIS, MONITORING AND TREATMENT OF CHILDREN’S HIP DISEASES
Perthes’ disease is an idiopathic osteonecrosis of a developmental hip that is most frequent in Northern Europe. Currently, the absence of a common set of standardized outcomes makes comparisons between studies of different interventions challenging. The overarching aim of this thesis was to …
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Temperaturentwicklung bei der Markraumbohrung : ein Vergleich verschiedener Bohrtechniken und Bohrsysteme
Hintergrund: Bei der Aufbohrung zur Marknagelung kommt es zur Entstehung von Reibungswärme. Es sind Fälle bekannt, bei welchen es zu Osteonekrose nach Aufbohrung kam. Anhand verschiedener Versuchsvorgaben soll hier geklärt werden, ob sich die beim Bohren entstehende Wärme durch einfache Methoden …
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Die Endoprothesenversorgung bei Hüftkopfnekrose : zementiert oder unzementiert? Ergebnisse unter Zuhilfenahme der EBRA-FCA
Von 1992 1998 wurden insgesamt 67 Patienten mit der Diagnose Hüftkopfnekro-se mit zementfreien Hüfttotalendoprothesen (n = 41; Mittleres Alter: 48,2 ± 9,1; m : w = 6 : 1, Alkohol, kortikoidinduziert, Idiopathisch: 6 : 7 : 15) oder zementier-ten Implantaten (n = 26, Mittleres Alter: 65,3 ± 8,4, m : …