Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Osteointegration"”.
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Multi-Scale Osteointegration and Neovascularization of Biphasic Calcium Phosphate Bone Scaffolds
… multi-scale porosity to promote multi-scale osteointegration, which may significantly improve scaffold mechanical properties and (2) human umbilical cord blood-derived endothelial colony forming cells have potential for promoting neovascularization in a bone defect when combined with rhBMP-2.
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Long-term osteointegration of BMP-2 eluting hydroxyapatite scaffolds for bone tissue engineering
… investigates a potential method to improve osteointegration of these hydroxyapatite bone scaffolds, the delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2). The objective of this study is to evaluate the effect of rhBMP-2 addition on scaffold osteointegration and degradation …
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Entfernung von Al2O3-Restpartikeln von der Oberfläche korundgestrahlter Titanimplantate durch die ALFREDS-Oberflächenbehandlung : Effekt auf die Biokompatibilität, Osteointegration und Scherhaftfestigkeit in-vivo
… was applied to quantify the amount of osteointegration. Statistical analysis was performed with ANOVA.RESULTS. Blinded histological and SEM analysis revealed the ALFREDS treatment to be fully biocompatible. All surfaces exhibited early bone repair, without differences of the …
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Optimising calcium phosphate cement formulations to widen clinical applications
… manipulated to maximise osteoconductivity and osteointegration of these CPC’s since the start of their commercialisation. Here in this thesis, a series of investigation are complied to demonstrate novel and inventive approaches to expand the application of CPC’s: (1) limiting the liquid phase …
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Microstructure and mechanical properties of biomedical alloys produced by Rapid Manufacturing techniques
… such porosity can favour cell adhesion and osteointegration. The most important intrinsic characteristic of RM techniques is the large undercooling the parts undergo during the process. This undercooling results in peculiar, very fine, metastable microstructures, associated to peculiar …
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The Effect of a Medial Collar on the Initial Stability of a Cementless Primary Femoral Hip Prosthesis
… may suffer as a result of the lack of long-term osteointegration due to early prosthesis instability. The present study demonstrates the effect of a medial collar on the initial stability of a triple-tapered, broach-only, proximally porous-coated primary cementless hip prosthesis using a …
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Towards an autologous tissue engineering construct for craniofacial bone repair
… for repair of these defects due to capacity for osteointegration and immunological compatibility. However, potential limitations, such as donor site morbidity, have motivated the development of alternative autologous approaches for the treatment of these defects. Materials used in tissue …
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Production of hard tissue scaffolds using three-dimensional printing method
… overcome limited donor availability and improve osteointegration. The aim of bone tissue engineering is to provide solutions to these problems by making available high quality transplants that can be supplied in larger quantities. In these applications both the internal and external geometry of …
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Design and Development of Novel Atomic Layer Deposition Equipment & Processes for Biomedical Applications
… in terms of hydrophobicity, cell response and osteointegration. The as-deposited films were characterized by spectroscopic ellipsometry (SE) for thickness and refractive index. Films were also characterized using X-ray Photoelectron Spectroscopy (XPS) to study its chemical composition. …
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Reduced order modelling of bone resorption and formation.
… new implant designs which encourage rapid osteointegration. There are a number of limitations with respect to previous research in the field of mathematical modelling of the bone remodelling process, including the absence of an osteocyte loop of regulation. It is within this context that …
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Nanolayer multi-agent scaled delivery from implant surface
… In rats, the successful growth factor-mediated osteointegration of the multilayered implants with the host tissue improved bone-implant interfacial strength by impressive amounts (15-fold) when compared with the bare implant control, and yields a mechanical bond 17-fold higher than that created …
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Biomimetic Materials for Biomedical Applications
… enhance the positive effect of HA coatings on osteointegration and bone regeneration, and prevent undesirable bone resorption. The possibility to introduce an active molecule in the implant site was explored using Matrix Assisted Pulsed Laser Evaporation to deposit hydroxyapatite nanocrystals …
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Prospective Clinical Study with New Materials for Tissue Regeneration: A Study in Humans
Objective: This study was performed to evaluate the clinical, radiographic, and histomorphometric outcomes of novel bone grafting materials and dental membranes and to compare the results with current data from literature. Materials and Methods: New synthetic bone substitutes, consisting of …
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Macro- and micro-structural features direct bone regeneration in patterned biphasic calcium phosphate scaffolds
The increasing demand for bone repair solutions for the treatment of large and load-bearing bone defects calls for the development of efficacious bone scaffolds. The design of such scaffolds involves a range of length scales from the centimeter down to the micron-scale. Biphasic calcium phosphate …