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Showing 1 to 4 of 4 for “"Osteoinductive potential"”.
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STUDIES IN THE DEVELOPMENT OF A XENOGRAFT-DERIVED BONE SCAFFOLD
… to alleviate the risk of bone graft harvest and potential for disease transmission. Xenografts sources are an attractive alternative because of their relatively unlimited supply from a pool of healthy donors but have historically been limited by the alpha-Gal epitope which may lead to immune …
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Engineering Musculoskeletal Tissue: In vitro and in vivo evaluation of novel scaffolds and growth factors for bone regeneration
… it is the only material that is osteoconductive, osteoinductive and osteogenic. Whilst effective, autologous bone grafting is limited by the finite amount of bone that can be safely harvested and by the unacceptably high complication rates. Aim: The aim of my research was to evaluate a number of …
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The Quantitative Assessment of Osteoinductivity of Human Demineralized Bone Matrix and cDNA Array Analysis of Osteogenic Differentiation in Human Periosteal Cells
… <em>in vitro</em> assays for determining the osteoinductive potential of human DBM and the use of cDNA gene expression array technology for examining gene expression profiles during osteoblast differentiation in human periosteal cells.</p> <p>BMP-4 is one of the most osteoinductive factors and …
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The Assessment of Osteoinductivity of Human Allograft Demineralized Bone Matrix by <i>In Vivo</i> and <i>In Vitro</i> Assay Models
<p>The osteoinductive potential (osteoinductivity) is a very important aspect of demineralized bone matrix (DBM) as a biomaterial. This study is directed at establishing qualitative and quantitative assays of the osteoinductivity of human DBM. Further aspects of this study include an assessment of …