Global ETD Search
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Showing 1 to 1 of 1 for “"Osteoarthritis, Rapamycin, Metformin, mTOR"”.
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The independent and combined effects of rapamycin and metformin on naturally occurring osteoarthritis
Osteoarthritis (OA) is among the top 10 diseases limiting human healthspan, and no disease modifying therapies currently exist. OA is a degenerative disease of the whole joint, characterized by articular cartilage loss, subchondral bone sclerosis, meniscal calcification, synovitis, and skeletal …