Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Osmotic pumps"”.
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Physiological Responses of Holstein Cows to Three Superovulatory Methods
… (FSH) administration subcutaneously (SC) via osmotic pumps, (2) assess the benefits of gonadotropin releasing hormone (GnRH) administration on the day of expected estrus and (3) determine the relationship of vaginal electrical resistance (VER) to the time of estrus and to other variables.
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Effects Of Sustained Release Somatostatin Type 2 Antagonism On Glucagon Counterregulation And Glycemia In Type 2 Diabetic Rate Model
… doses of ZT-01 or vehicle using implanted mini-osmotic pumps. While ZT-01 did not significantly affect basal glucose levels or oral glucose tolerance, it tended to increase baseline glucagon levels and the glucagon response to insulin-induced hypoglycemia, though the effects were small. Overall, …
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The effect of continuous infusion of human parathyroid hormone on bone architecture in female mice
… subsequently study the catabolic effects of PTH. Osmotic pumps were implanted subcutaneously and infused either vehicle, 40 pg/kg/day of PTH or 80 pg/kg/day of PTH for either 2 week or 4 week duration. Total body bone mineral density (BMD) and bone mineral content (BMC), trabecular and cortical …
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Group IV Cytosolic Phospholipase A2α Is Critical for the Development of Angiotensin II-Induced Hypertension and Associated Pathogenesis
… effect of Ang II infusion for 13 days by micro-osmotic pumps (700 ng/kg/min), on systolic blood pressure and associated pathophysiological changes in wild type (cPLA2α+/+) and cPLA2α-/- mice. Ang II infusion increased systolic blood pressure in cPLA2α+/+ but not in cPLA2α-/- mice. Ang II induced …
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Combined chemotherapy and immunotherapy against experimental malignant brain tumors
… mice when delivered intratumorally using micro-osmotic pumps. When immunization with irradiated GM-CSF-producing tumor cells is combined with intratumorally administered TMZ, the survival of tumor-bearing mice is synergistically enhanced, while systemic delivery of TMZ abrogates the effect of …
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Biological role of conceptus derived factors during early pregnancy in ruminants
… elongation. Gene knockout studies utilizing osmotic pumps to deliver morpholino antisense oligonucleotides, lentiviral transduction of shRNAs, and CRISPR/Cas9 based genome editing were used to target the conceptus during elongation. Results of the studies established that: (1) IFNT is not …
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Cytochrome P450 1B1 and 12/15 Lipoxygenase Interaction in Paraventricular Nucleus in Angiotensin II-induced Hypertension in Females
… II (700 ng/kg/min) was infused subcutaneously by osmotic pumps for 2 weeks evaluation of hypertension and associated pathogenesis. Blood pressure (BP) was measured by tail-cuff and confirmed by radiotelemetry. Adenoviral probes including adenovirus (Ad)-green fluorescence (GFP)-ALOX15-short …
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Biodegradable, Liquid-Filled, Spherical Capsules With Pre-Determined Burst Times
… shell thickness, radius of the capsule, core osmotic pressure and the membrane tensile strength. Elastoplastic and failure characterization of PLGA was conducted as a function of hydration under uniaxial and biaxial stretch and by a novel “beach ball” inflation technique. The presence of small …
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Development and Characterization of a Recombinant Vesicular Stomatitis Virus (rVSV) for the Treatment of Glioblastoma
… continuous infusion of virus using implantable osmotic pumps, and pre-infected autologous carrier cells. These methods were designed to enhance anti-tumor effect by managing the negative effects of the tumor microenvironment and of a functional immune system on viral therapy. Results and …