Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Osmotic mini-pump"”.
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Systemic Blockade of the Endocannabinoid System Alters Gene Expression and acquisition of a Hippocampus Dependent Learning Task
… Pharmacology It has been established that the administration of Δ9-THC and other cannabinoid agonists results in disruptions in learning and memory (Sullivan, 2000). The ability of rimonabant to reverse memory deficits induced by cannabinoid agonists lead to the hypothesis that administering it …
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Evaluation of agonist pharmacotherapy for cocaine dependence: effects of continuous d-amphetamine treatment on cocaine self-administration in rats
… Thus far, studies have shown that the route of administration and treatment regimen greatly influence the therapeutic effectiveness of d-amphetamine in that continuous, but not acute, administration of d-amphetamine decreases the reinforcing effects of cocaine. The studies presented in Chapters II …
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Stimulating angiogenesis into biomaterials through the delivery of growth factors
… in rats. The construct consisted of an osmotic mini pump and a tube of porous PU lined with ePTFE, into which a defined amount of VEGF16s was pumped for 10 days. After implantation, granulation tissue was growing into the pores of the PU and neovascular area was increased up to 265 % …
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Mise en évidence du rôle physiologique de la chimiokine CCL2 dans la neurotransmission nociceptive au niveau spinal
… both provoked and spontaneous pain by 50% when administered i.t. We also observed that spinally blocking CCR2 limited the expression of proinflammatory mediators. It also reduced peripheral inflammation by preventing peripheral transport of SP. We then translated our findings in a model of …