Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Oropharyngeal candidiasis"”.
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Towards a more efficacious treatment for Oropharyngeal Candidiasis (OPC): Hydrogel-forming tablets for the controlled release delivery of Chlorhexidine diacetate
Oropharyngeal candidiasis is a localised infection in the oropharynx region caused by Candida species, predominately C. albicans. It is commonly spread among immunocompromised patients and aggravated by hyposalivation or xerostomia. Current treatment is by systemic antifungals, which might be …
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Mechanism of Candida Albicans Biofilm and Virulence Inhibition By A Bacterial Secreted Factor
… is protective in the murine macrophage and oropharyngeal candidiasis (OPC) infection models at nanomolar concentrations. Epithelial invasion, inflammation, and fungal burden in the OPC model were significantly reduced in response to treatment with EntV<sup>68</sup>. Collectively, <em>C. …
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Signal Transduction and Transcriptional Regulation Pathways Essential for Azole Resistance in Candida albicans
… of diseases, including the mucosal infection oropharyngeal candidiasis (OPC) which frequently effects patients with human immunodeficiency virus (HIV). The azole antifungals (such as fluconazole) are the most widely used and important ergosterol biosynthesis inhibitors (EBIs) for the treatment …
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The Impact of Candida albicans Glycogen on Fitness, Virulence and Host Response
… that presents in healthy persons colonizing the oropharyngeal, esophageal, and gastrointestinal mucosa. This polymorphic fungal pathogen remains a leading cause of both invasive and superficial mycoses. C. albicans can cause oropharyngeal candidiasis (OPC) and disseminated candidiasis when normal …
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Transcriptional Regulation of Azole Antifungal Resistance in Candida albicans
… and urogenital tracts of humans. Oropharyngeal candidiasis (OPC), an opportunistic mucosal infection caused by C. albicans, occurs most frequently in patients infected with human immunodeficiency virus (HIV). OPC is usually treated with azole antifungals, a class of antifungals …