Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Orc"”.
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Relocation of ORC to OR2
… after operating room for cesarean sections (ORC) is relocated from obstetric unit to the main operating room (OR). The microsystem will accomplish this through effective teamwork, clear interdisciplinary communication, collaboration, and standardization of processes involved. The institution …
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Real gas effects in ORC turbines
… on turbine performance. Most prominently ORC turbines are operating with a multitude of different working fluids that have very strong variations in gas properties. Moreover, this also applies to conventional steam turbines or first stage HP turbines with very high temperatures, where the …
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An ORC Flip Enables Bidirectional Helicase Loading
… loading. The origin-recognition complex (ORC) recognizes and binds origin DNA and recruits Cdc6. Mcm2-7 in complex with a third protein Cdt1 associates with ORC/Cdc6/DNA. Cdc6 and Cdt1 are sequentially released to allow loading of an oppositely-oriented second Cdt1-bound-Mcm2-7 hexamer …
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Role of ORCA and ORC in chromatin organization and DNA replication
In eukaryotes, Origin recognition complex (ORC) proteins establish the pre-replicative complex (pre-RC) at the origins and this is essential for the initiation of DNA replication. In human cells, ORC is a highly dynamic complex with many separate functions attributed to sub-complexes or individual …
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The Scarlette Saga Volume I: The Education of Half-Orc Scarlette Urrug
The Education of Half-Orc Scarlette Urrug The Education of Half-Orc Scarlette Urrug: Volume I (EHSU) experiments with form and consists of three interwoven plotlines: social, familial, and educational. The idea to experiment with EHSU's formatting arose from a desire to immerse readers in …
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The role of Orc6 in ORC binding-site switching during helicase loading
… during which the origin recognition complex (ORC) coordinates loading of two Mcm2-7 hexameric helicases in opposite orientations to form the Mcm2-7 double hexamer. These Mcm2-7 double hexamers mark sites of eventual bidirectional replication initiation upon entering S-phase, when activation of …
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Changing protein-DNA interactions promote ORC binding site exchange during replication origin licensing
… loader, the origin- recognition complex (ORC), sequentially loads two Mcm2-7 hexamers in the precise orientation required for bidirectional replication. ORC initiates this process by binding to a high-affinity DNA binding site to load the first Mcm2-7 hexamer. Subsequently, ORC transitions …
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Charge-sensitive methods for the off-design performance characterization of organic Rankine cycle (ORC) power systems
The organic Rankine cycle (ORC) is among the most suited technologies to convert low-grade and low-capacity heat sources into useful work. For many reasons - including predictive control, optimal sizing or performance forecast - a proper understanding and characterization of the ORC behaviour under …
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Digital Supply Chain Connectivity and Capacity Analysis for Strategic Production Planning in Biosurgery Oxidized Regenerated Cellulose
… within its Oxidized Regenerative Cellulose (ORC) product line. This increase in demand is causing challenges within the current ORC value stream as production dynamics and manufacturing capacities are being stretched to meet growing consumer needs. In addition, the ORC digital data thread is …
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Qualidade de vida no trabalho e o potencial de flexibilidade estrutural no SENAI CEP/ORC: Centro de Educação Profissional Odilon Ribeiro Coutinho.
… estrutural no contexto da empresa SENAI CEP/ORC, empresa esta, considerada modelo em relação à aprendizagem e capacitação para a indústria do Brasil, com mais de 70 anos de história, estando presente em todas as regiões do país. Segundo a natureza dos dados a pesquisa é quantitativa e …
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ORCA/LRWD1, a novel player in the initiation of eukaryotic DNA replication
… assembly includes an ordered recruitment of ORC, Cdt1, Cdc6, and the helicase MCMs to replication origins, and is strictly governed by replication licensing system. As the complexity increases dramatically from yeast to human cells, additional replication regulators have been identified in …
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Feasibility of using power steering pumps in small-scale solar thermal electric power systems
… feed pump in a 1-kWe organic Rankine cycle (ORC) system built by the Solar Turbine Group in Lesotho. The pumps tested included OEM plunger and piston pumps, and rotary vane-type power steering pumps purchased from a junk yard. Motor speed and torque were measured at different flow rates to …
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A Unified Theory Characterising the Spontaneous Condensation Tendency of Working Fluids in Organic Rankine Cycle Expansion: Key Difference from Steam and its Implications
… fluids during a typical Organic Rankine Cycle (ORC) expansion from slightly superheated condition or dry-saturated condition directly into the saturation dome, in the context of an ORC expander. Traditional wisdom on steam Rankine cycles dictates that the expansion process be almost completely …
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Analysis of metazoan DNA replication initiation using Drosophila gene amplification as a model system
… localization of the origin recognition complex (ORC) on a genome-wide level and observed that, at the start of synchronous amplification, ORC localizes to the six amplicons with levels corresponding to the magnitude of amplification. Additionally, we investigated amplification with respect to …
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Treatment of Ischemic Equine Jejunum with Topical and Intraluminal Carolina Rinse
… blood flow, osmotic reflection coefficient (ORC), wet weight to dry weight ratios (WW/DW), and neutrophil accumulation in the serosa were measured. ORC is defined as the lymph protein concentration to plasma protein concentration ratio subtracted from one (1- Cl / Cp) at maximal lymph flow. …
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The design and analysis of radial inflow turbines implemented within low temperature organic Rankine cycles
… surge of interest in organic Rankine cycles (ORC). With the ability to convert low temperature heat sources into power, ORC technology is at the forefront of many sustainable technologies such as biomass, solar, geothermal and waste heat recovery. Despite successful commercialisation for …
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Role of WD domain-containing proteins in cell cycle progression
… how two WD domain-containing proteins, LRWD1/ORCA and RFWD3, regulate different aspects of cell cycle progression. In eukaryotic cells, the duplication of the genome starts from the loading of a six-subunit complex, Origin Recognition Complex (ORC), onto replication origins on the chromosome. …
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Design And Optimization Of Organic Rankine Cycle For Low Temperature Geothermal Power Plant
… power generation. Organic Rankine Cycle (ORC) technology makes it feasible to use low temperature resources to generate power by using low boiling temperature organic liquids. The first hypothesis for this research is that using ORC is technologically and economically feasible to generate …
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Impact of DNA accessibility and sequence on eukaryotic origin licensing
… three proteins, the origin-recognition complex (ORC), Cdc6, and Cdtl, as well as the DNA sequence present at potential origins. Although in S. cerevisiae, ORC binds to a known DNA sequence, where the other proteins, particularly the Mcm2-7 helicase, interact with DNA is not known. To gain …
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Rewriting-based formal modeling, analysis and implementation of real-time distributed services
… logic, the Maude system, and the theory of Orc, with the overall goal of improving the reliability of Internet software. The dissertation focuses on the formal specification and analysis of two fundamentally important aspects of Internet software systems: (1) the correctness of service …
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