Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Oral squamous cell carcinoma (OSCC)"”.
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Development of Electrochemical Immunosensor for Oral Cancer: Initial Outcome
Oral Squamous Cell Carcinoma (OSCC), accounting for nearly 90% of head and neck malignancies, continues to pose a global health challenge with over 250,000 new cases annually, especially in developing nations. Its frequent progression from precancerous lesions such as oral leukoplakia (OL) …
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Innovating surgery for oral squamous cell carcinoma with targeted fluorescent and magnetic tracers
Oral squamous cell carcinoma (OSCC) is characterised by its locally aggressive nature and its high propensity to metastasise to regional lymph nodes (LN)s. It is well-established that margin status and the presence of LN metastases are two of the most important factors affecting prognosis. While …
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SURGICAL TREATMENT OF ORAL LEUKOPLAKIA: A RANDOMIZED CONTROLLED CLINICAL TRIAL COMPARING SURGERY WITH WAIT AND SEE APPROACH
… proposed for the management of the most common oral potentially malignant disorders (i.e., leukoplakia and erythroleukoplakia) in order to prevent the risk of oral cancer. However, there is currently no consensus on the most effective approach for the patients affected by such lesions. Surgery …
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Defining mechanisms directing YAP/TAZ-mediated tumorigenesis
… a range of epithelial-derived cancers, including oral and breast cancers, but their downstream targets and mechanisms of action are unclear. Recent studies have suggested that the pro-tumorigenic roles for YAP/TAZ relate to their convergence with growth factor signaling pathways. Based on these …
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EVALUATING THE CHEMOTHERAPEUTIC EFFECTS OF SR9009 AND ESOMEPRAZOLE ON ORAL SQUAMOUS CELL CARCINOMA USING CIRCADIAN-TAILORED INNOVATIVE THERAPEUTIC APPROACHES
The vast majority (95%) of oral cancer, which has an overall 5-year survival rate of 66%, is oral squamous cell carcinoma (OSCC). New potential triggers, including circadian clock disruption that is caused by multiple lifestyle traits such as chronic gastroesophageal reflux and human papillomavirus …
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The expression and role of Migration Stimulating Factor (MSF) in oral tumours
… produced by both epithelial and stromal cells during foetal development, not expressed by the majority of their normal adult counterparts, but re-expressed during pathological processes such as cancer and wound healing. Scotland has the highest occurrence of oral cancers in the UK; the …
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HPV and p16 in head and neck cancer
… (HPV) may play a causal role in head and neck carcinoma (HNSCC). The aim of this study was to investigate the prevalence of HPV DNA in HNSCC and to determine whether any correlation exists with p16 or survival. An initial pilot study of sixty formalin-fixed HNSCC was carried out in order to …
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Perineural Invasion in Oral Squamous Cell Carcinoma and Salivary Gland Malignancies: Incidence, Prognostic Impact and Molecular Insight
… incidence rates of perineural invasion (PNI) in oral squamous cell carcinoma (OSCC) and salivary gland malignancies (SGMs) worldwide. PNI exhibited by some OSCC and SGMs has been known as an independent predictor of poor prognosis and an indicator of aggressive behaviour. Furthermore, the …