Global ETD Search
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Showing 1 to 8 of 8 for “"Optical stretcher"”.
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On the theory of the optical stretcher : optics, mechanics, and thermal effects
The optical stretcher (OS) is dual-beam laser trap capable of capturing and deforming micron-sized particles or biological cells. It can be employed to measure cell-mechanical properties and, thus, to monitor physiological changes, such as differentiation, and to diagnose diseases that affect the …
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Hybrid Ray Optics and Continuum Mechanics Modeling of Cell Deformation in the Optical Stretcher
Since the invention of the optical stretcher in 2001, no direct method has been found for measuring the optical stress that produces the observed trapping and stretching of biological cells and other dielectrics. Hence, mathematical and computational models have been developed to calculate the …
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Optical deformability : micromechanics from cell research to biomedicine
… on the surface of a transparent object, the optical surface forces, generated by the interaction of the light with the material, are directed away from the denser material and normal to its surface. This physical phenomenon can be used to probe the mechanical properties of dielectric …
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Cell compliance: cytoskeletal origin and importance for cellular function.
… and can be measured with a dual-beam laser trap (optical stretcher). Functional changes, which go hand in hand with changes of the cytoskeleton, also occur during differentiation of stem cells. This suggests monitoring differentiation by the changing compliance of the cells. During the course of …
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Homeostasis and volume regulation in the Plasmodium falciparum infected red blood cell
… infected red cells were studied using a novel optical stretcher device, which enabled individual cells to be trapped and manipulated optomechanically in microfluidic channels. Combined, these methods offered a unique insight into the homeostatic and rheological behaviour of malaria-infected red …
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The dynamics and optimization of the radiation of a femtosecond diode pumped Yb:KGW laser /
… this method the scale of pulse stretching in the optical stretcher depends only on the beam size and the diffraction grating grooves density and does not depend on the bandwidth of the pulse. In order to optimized the compression of amplified pulses we have also proposed and experimentally tested …
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Effect of Cell-Substrate Interactions on Epithelial Cell Mechanics
… atomic force microscopy and a microfluidic optical stretcher. We found that adherent cells stiffen and suspended cells soften with the expression of constitutively active Ras. The effect on adherent cells was reversed when contractility was inhibited with the ROCK inhibitor Y-27632, …
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Dynamics and Mechanics of Zebrafish Embryonic Tissues
… and interfacial tensions. In chapter 6, an optical stretcher device is applied to measure, solely by means of laser light, the material properties of individual cells. Hereby it is shown that single cells from the two investigated tissue types differ in their mechano-physical properties. …