Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 136 for “"Optical coherence tomography (OCT)"”.
-
Optical domain subsampling for data-efficient optical coherence tomography (OCT)
Recent advances in optical coherence tomography (OCT) have led to higher-speed sources that support imaging over longer depth ranges. Limitations in the bandwidth of state-of-the-art acquisition electronics, however, prevent adoption of these advances into clinical applications. This thesis …
-
Micro-motion detection by optical coherence tomography (OCT) and its clinical applications
… imaging techniques, this thesis focused on optical coherence tomography (OCT) and in particular on phase-sensitive optical coherence tomography (PhS-OCT). In this thesis, a PhS-OCT system is developed for micro-motion detection and a dual camera PhS-OCT system is developed to double the …
-
Digital signal processing techniques for optical coherence tomography : OCT and OCT image enhancement
… and image quality of ultrahigh resolution optical coherence tomography (OCT) systems. To reduce the dependence of OCT research systems on fixed analog electronics and to improve overall system flexibility, a digital demodulation scheme implemented entirely in software was developed. This …
-
Development of a three-dimensional camera based on subsampled optical coherence tomography (OCT)
Optical coherence tomography (OCT) allows label-free, three-dimensional imaging of tissue structure. Current implementations of OCT can either image over long depth ranges at slow imaging speeds, or over limited depth ranges at high speeds. Here, we describe a new OCT paradigm that supports …
-
Multifocal interferometric synthetic aperture microscopy
… synthetic aperture microscopy (ISAM) to optical coherence tomography (OCT) data collected with multiple positions of the focal plane. Multifocal ISAM achieves spatially invariant resolution like ISAM by applying the solution of the inverse problem to the forward model for each channel. A …
-
Methods to Tailor Protein Microspheres for Biomedical Applications
… have resulted in the first class of optical contrast agents for optical coherence tomography (OCT). Modifications with receptor specific peptides have generated microspheres that can be targeted to tumor cells. And finally, modifications of the microspheres with nucleic acids have …
-
Analytical Modeling of Optical Coherence Tomography
Optical Coherence Tomography (OCT) has become an indispensable imaging modality in ophthalmology and dermatology, prized for its micrometer-level resolution, non-invasiveness, and significant penetration depth. Despite its precision in revealing skin morphology, standard OCT lacks the ability to …
-
DEEP LEARNING ALGORITHMS FOR OPTICAL COHERENCE TOMOGRAPHY IMAGES WITH APPLICATIONS IN GLAUCOMA
… clinically treatable one. Since the inception of optical coherence tomography (OCT) technology, it has been possible for the in vivo assessment of these morphological changes in both the neural and connective tissues of the ONH. Nevertheless, it has been possible to use only a single neural tissue …
-
Optical coherence tomography applied to investigations of optical properties of paintings
Optical Coherence Tomography (OCT), a fast 3D scanning Michelson interferometer normally applied to biomedical applications has recently been applied to art related subjects. In this thesis, the various applications of OCT to the non invasive imaging of paintings are explored in detail. The …
-
High-speed polarization-sensitive optical coherence tomography: toward intraoperative cancer imaging
… for real-time assessment of the tumor cavity. Optical coherence tomography (OCT) has previously been developed for real-time intraoperative use in hopes of aiding tumor margin assessment. While there has been much success, it remains difficult to distinguish between normal stroma tissue and …
-
Phase-sensitive light : coherence theory and applications to optical imaging
… biphotons. SPDC has been utilized in a number of optical imaging applications, such as optical coherence tomography, ghost imaging, holography and lithography, to obtain performance that cannot be realized with standard optical sources. However, a debate continues as to whether the improved …
-
Transformer-Based Prediction of Coronary Artery Lumen Expansion Post Angioplasty Using Optical Coherence Tomography
… lumen area prediction from pre-stenting optical coherence tomography (OCT) images. This pipeline includes morphological correction of OCT image segmentations, explainable feature extraction from OCT segmentations, and a predictive transformer network that combines morphological features …
-
Optical frequency domain imaging of human retina and choroid
Optical coherence tomography (OCT) has emerged as a practical noninvasive technology for imaging the microstructure of the human eye in vivo. Using optical interferometry to spatially-resolve backreflections from within tissue, this high-resolution technique provides cross-sectional images of the …
-
Ultrahigh resolution optical coherence tomography for the detection of early stage neoplastic pathologies
… significantly improve treatment outcome. Optical coherence tomography (OCT) is an emerging biomedical imaging technique that can potentially be used as an in vivo tool for identifying early stage neoplastic pathologies. Recent advances in solid-state laser and nonlinear fiber technology …
-
Volumetric Optical Imaging of Tissue Microstructure for Grading of Dysplasia In Vivo
Optical imaging offers unique advantages in medical diagnostics. In particular, high resolution, fast imaging speed, and strong depth penetration make optical coherence tomography (OCT) an attractive modality for non-perturbatively investigating structural changes in tissue that accompany disease …
-
RF test methods for balanced receivers for swept source optical coherence tomography
Optical coherence tomography (OCT) has risen as a clinical standard of diagnosis and management of ocular diseases since its development in 1991 by the MIT group and the collaborators. Since current cutting-edge OCT technology based on frequency-swept lasers has achieved scanning rate over …
-
1.2-micron multi-section quantum dot superluminescent diodes
… of skin tissue especially in the field of optical coherence tomography (OCT). In this thesis a ridge-waveguide multi-section quantum dot SLD that emits at 1.2μm with a bandwidth greater than 100nm and a power greater than 0.2mW is presented. The multi-section SLD allows simultaneous tuning …
-
Characterization and comparison of optical source relative intensity noise and effects in optical coherence tomography
This thesis research investigates the effects of optical source noise in optical coherence tomography (OCT). While shot noise, thermal noise and relative intensity noise (RIN) (excess photon noise) constitute optical noise, RIN is the least understood and often the most significant factor limiting …
-
Information extraction algorithms based on optical coherence tomography data
… we present several algorithms developed for optical coherence tomography (OCT) datasets. We show that by incorporating physical modeling, mathematical analysis and signal processing, it is possible to uncover the huge potential hidden in the raw OCT data. The automated Interferometric …
-
Tactile sensing of shape : biomechanics of contact investigated using imaging and modeling
… together with their deformation patterns, optical coherence tomography (OCT) was used to image human fingertips in vivo, free of load as well as when loaded with rigid indenters of different shapes.
Page 1 of 7