Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Optical Coherence Elastography"”.
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Magnetomotive optical coherence elastography for biomedical applications
This thesis presents a new non-invasive optical method for assessing biomechanical properties of tissues and cells in real time and with micron scale resolution, magnetomotive optical coherence elastography (MM-OCE). Biomechanical properties are important because they relate to the tissues’ state …
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Characterizing Corneal Biomechanical Properties Using Dynamic Optical Coherence Elastography
Purpose: Optical coherence elastography (OCE) quantifies the tissue’s biomechanical properties through mechanical loading and imaging the tissue response using optical coherence tomography (OCT). Current techniques evaluating corneal stiffness do not account for the influence of key physiological …
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Assessing the Biomechanical Properties of Cornea using Optical Coherence Elastography
… biomechanical properties of cornea based on low-coherence optical imaging, focusing on optical coherence elastographic techniques, to meet the growing demand for noninvasive high-resolution tissue characterization with improved diagnosis and treatment of ocular diseases. The research work was …
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Heartbeat Optical Coherence Elastography: A Method for Passive Biomechanical Assessment of the Cornea
… analysis technique termed heartbeat optical coherence elastography (Hb-OCE). This technology enables mechanical characterization of the cornea with applications in disease detection, staging, and therapeutic monitoring. This dissertation explores the development and evolution of the …
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Development of Surface Acoustic Wave Optical Coherence Elastography (SAW-OCE) for Soft Tissue Characterisation
… modalities such as the magnetic resonance elastography (MRE) and the ultrasound elastography to quantify the mechanical properties. Although the magnetic resonance imaging (MRI) and the ultrasound imaging can penetrate deep inside the human body, the millimetre-scale spatial resolution has …
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Elastic Characterization of <i>ex vivo</i> Human Prostate Tissue Using Vibration Optical Coherence Elastography and Second Harmonic Generation Microscopy
… This research work aims to apply two emerging optical imaging modalities to quantitatively evaluate the degree of malignancy.<br/><br/>This research thesis presents the vibration optical coherence elastography (OCE) to quantify the tissue stiffness on a microscopic scale. A feasibility study of …
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Coherence imaging technologies for the measurement of tissue and cell biomechanics
… falls at the intersection of biomechanics and optical imaging, and focuses on optical elastography, an optical sensing and imaging technique used to measure biomechanical properties at the tissue and cell levels. Optical coherence elastography, multiphoton elastography, and magnetomotive …
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Micro-motion detection by optical coherence tomography (OCT) and its clinical applications
… has various applications such as ultrasound elastography and magnetic resonance elastography (MRE). Ultrasound transducers, the most commonly used tool to detect endogenous and exogenous micro-motions, have a number of drawbacks: including the requirements of the physical contact with the …
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Characterization of in vivo human skin in response to mechanical indentation using optical coherence tomography
… tissue characterization is highly desirable. Optical coherence tomography (OCT) is an interferometry-based imaging modality that offers an imaging resolution (cellular level) that surpasses those of most standard clinical imaging tools and has shown to be able suitable for in vivo skin …
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Magnetomotive optical coherence tomography and elastography with applications in magnetic thermotherapy dosimetry
… which can be detected via magnetomotive optical coherence tomography (MM-OCT) and enable biomechanical characterization with magnetomotive optical coherence elastography (MM-OCE). In this thesis, the theranostic functionality of MNPs are exploited, where the biomechanical alterations of …
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Multi-Functional Optical Coherence Tomography Assesses Skin Involvement in Systemic Sclerosis
… focuses on developing a novel technique utlizing optical coherence tomography (OCT) to assess the skin's morphological, mechanical, and microvascular characteristics in SSc patients. OCT is a noninvasive imaging modality with optimal depth (1-2 mm) and resolution (5-15 μm) for detailed …
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Clinical Translation of Dynamic OCE for Corneal Biomechanical Assessment
… aims to clinically translate dynamic optical coherence elastography (OCE) for spatially-resolved quantification of human corneal biomechanics in vivo. Methods: An air-pulse–based OCE system was adapted for noninvasive clinical assessment of corneal elastic modulus. Corneal mechanical …
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Shear Wave Elastography Based on Optical Coherence Tomography
… mechanical property, numerous research works in elastography have been conducted and had been successfully applied to countless clinical applications. Elastography techniques had been always rooted in medical imaging technique, classified into a range of scales, based on their imaging depth and …
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Development of UK legislation Guidance for Research Medical and In Vitro Diagnostic Devices
… A case study of the research project – ‘the ‘Optical Coherence Elastography’ system, will be undertaken to gain an understanding of the regulatory documentation required.<b><br/></b><b><br/></b><b>Results</b>: The development of documentation that must be followed by academics and third …