Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Optic Nerve Head"”.
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Optic Nerve Head Image Analysis for Glaucoma Progression Detection
… care. In the glaucoma clinic, retinal and optic nerve head (ONH) imaging can be used to help the clinician to manage patient treatment appropriately. By providing high resolution images of the optic nerve head structures and identifying changes therein related to disease onset and …
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Biomarkers of Optic Nerve Head Glial Cell Activation Following Biomechanical Insult
… death of retinal ganglion cells, a unique optic nerve neuropathy resulting in loss of vision. Increased intra-ocular pressure is known to be a leading risk-factor for glaucoma, and lowering IOP is currently the only evidence based method for the clinical management of the disease. However …
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Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes
… of glaucoma. However, their impact on optic nerve head (ONH) structure in normal eyes has not been fully described. We examined whether differences exist in ONH and lamina cribrosa structure with myopia in older normal eyes. Methods: Spectral domain optical coherence tomography (SDOCT) …
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Bestimmung von arteriovenöser Passagezeit, Farbstoffbolusgeschwindigkeit und Steigung des Farbstoffeinstroms sowie Berechnung des okulären Blutflusses in den retinalen Blutgefäßen bei Normaldruckglaukompatienten mittels Scanning-Laser-Fluoreszein-Angiographie
Circulatory deficits around the optic nerve head are a primary factor in the pathogenesis of the Normal-Tension-Glaucoma. In this study AVP and FBG were measured and as in previous studies a slower velocity in NDG-Patients. However, the ocular blood flow is of primary importance for the nutrition …
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Finite element modeling of the human eye
… and magnitude of peak stresses in the retina and optic nerve head during initial loading. After 0.6125 ms, stresses as high as 5.4 x 10⁷ Pa were reached. The peak stresses occurred in the portions of the retina and the optic nerve head close to the boundary between these two substructures.
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Leckage der Papille bei gesunden Probanden und Glaukompatienten mittels Scanning-Laser-Ophthalmoskop-Videofluoreszenzangiographie
The investigation of the optic disc and their changes is probably the most important process parameter with glaucoma and glaucoma-suspicion. By numerous picture giving procedures one strives since the beginnings of the ophthalmology to regard the eye background with glaucoma patients in order to …
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Following Ocular Changes in United States Optometry Students (FOCUS): Protocol Development and Baseline Data
… (Grand Seiko), biometry (LenStar), optical coherence tomography (OCT) and OCT angiography (OCTA, Spectralis), and ocular aberrations (COAS HD). Participants were classified into refractive error groups. OCT scans were analyzed for retinal and choroidal thickness, optic nerve head …
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Structural Integrity of Eyes Diagnosed with Amblyopia. The measurement of retinal structure in amblyopia using Optical Coherence Tomography.
… to establish the prevalence of subtle retinal/optic nerve head defects in eyes diagnosed with amblyopia, to distinguish between possible explanations for the origin of such defects and to investigate the relationship between quantitative measures of retinal structure, retinal nerve fibre layer …
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Structural Integrity of Eyes Diagnosed with Amblyopia. The measurement of retinal structure in amblyopia using Optical Coherence Tomography.
… to establish the prevalence of subtle retinal/optic nerve head defects in eyes diagnosed with amblyopia, to distinguish between possible explanations for the origin of such defects and to investigate the relationship between quantitative measures of retinal structure, retinal nerve fibre layer …
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DEEP LEARNING ALGORITHMS FOR OPTICAL COHERENCE TOMOGRAPHY IMAGES WITH APPLICATIONS IN GLAUCOMA
… in complex 3D biomechanical changes of the optic nerve head tissues (ONH), is indeed a well-known risk factor and considered as the only clinically treatable one. Since the inception of optical coherence tomography (OCT) technology, it has been possible for the in vivo assessment of these …
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Evaluating The Estimation of Neuronal Loss in Glaucoma
PURPOSE: In vivo imaging with optical coherence tomography (OCT) is widely used in the diagnosis and monitoring of glaucoma and other optic neuropathies. With spectral domain OCT (SD OCT), cross-sectional images of the retinal nerve fiber layer (RNFL), optic nerve head (ONH) and the macula can be …
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High-speed Fourier domain Optical Coherence Tomography for structural and functional imaging of the retina
Optical Coherence Tomography (OCT) is an emerging optical biomedical imaging technology that enables cross-sectional imaging of scattering tissue with high sensitivity and micron-scale resolution. In conventional OCT, the reference arm path length in a Michelson interferometer is scanned in time to …
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Knowledge Mining In The Clinical Assessment Of Glaucoma
… be characterized by structural changes in the optic nerve head (ONH) and retinal nerve fibre layer (RNFL) that can be evaluated by various retinal-imaging techniques such as scanning laser polarimetry and optical coherence tomography (OCT). The structural damage can lead to functional damage in …
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Glial Changes and Role of Connexin43 in a Laser-induced Rodent Model of Retrobulbar Optic europathy
Purpose: To establish a novel model of rodent optic nerve damage in order to investigate glial changes occurring in retrobulbar portion of the optic nerve after the injury and to facilitate development of neuroprotective agents. Methods: Rats (200-250g) were first anaesthetised via intraperitoneal …
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A study of case finding for chronic open angle glaucoma by UK community optometrists
… is largely based on a triad of tests: optic nerve head assessment, tonometry, and visual fields. There has been little research into optometrists’ COAG case-finding strategies. Chapter 2 reports on a national survey regarding COAG case-finding methodologies and referral criteria. Survey …
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Bedeutung zirkulatorischer retinaler Ergebnisse zur Differenzierung des Normaldruckglaukoms vom primären Offenwinkelglaukom
… in the perfusion and lesser perfusion of the optic nerve head are considered to be the cause. Wether these come into existence or are a secundary consequence of the increase in intraocular pressure, is still left to discussion. In general the open-angle glaucoma is rather attributed to the …
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Fluoreszein-Angiographie und Progression des Glaukoms
… western world, characterized by damage of the optic nerve and visual field loss. Various theories have been proposed to explain the pathogenesis of glaucoma. The pathogenetic concepts may be divided in a mechanical, pressure-related and a vascular approach. In the vascular theory a low …
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Longitudinal Evaluation of Retinal Capillaries in Experimental Glaucoma
… RPC perfusion relate to changes in the retinal nerve fiber layer (RNFL) over time in a non-human primate (NHP) model of experimental glaucoma (EG). Methods: First, the longitudinal repeatability of quantifying manually segmented RPCs acquired using adaptive optics scanning laser ophthalmoscope …
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The Impact of a Scleral Lens on the Eye
… LZR changes the intraocular pressure (IOP) and optic nerve head minimum rim width (MRW). Methods: (1) In normal subjects (n=15) wearing SL for 8-hour, basal and FR tear samples were collected, and immunomodulatory molecules were quantitated using Luminex multiplex immunoassay and compared …
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A novel particle-based in situ gelling system for delivering hydrogen sulfide at a sustained rate for potential application in glaucoma and retinal neurodegeneration
… neurodegeneration of retina ganglion cell and optic nerve head. If left untreated it may cause blindness. Current therapies help in lowering the IOP, however, it is the neurodegeneration which plays a key role in blindness. Hydrogen sulfide functions both as a neuroprotectant and IOP lowering …
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