Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Opiates."”.
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The Impact of Opioids and Opiates on Adult Hippocampal Neurogenesis
… findings support a negative role for opioids and opiates in regulating adult hippocampal neurogenesis.
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An evaluation of analytical procedures for detection of drug abuse with particular reference to opiates.
… benzodiazepines, cannabinoids, cocaine and opiates involving some 1400 subjects by enzyme immunoassay, carried out by the author, are reported. The corresponding confirmatory tests by GC-MS on samples screening positive by immunoassay are also reported. Deficiencies in the immunoassay screen …
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Searching for potential markers for monitoring the presence of opiates in urine exposed to oxidising adulterants
… project has shown that following exposure of six opiates (6-MAM, morphine, codeine, codeine-6-glucuronide, morphine-3-glucuronide and morphine-6-glucuronide) to various oxidising adulterants (nitrite, PCC and hypochlorite), stable reaction products were identified in urine. The structures of 12 …
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CNS Neural/Glial Progenitors as Targets of HIV-1 and Opiates: Effects on Proliferation and Population Dynamics May Alter Behavior Outcomes.
… progenitors may be targets of HIV proteins ± opiates drugs of abuse. To determine whether progenitors are targets of HIV-1, a multi-plex assay was performed to assess chemokine/cytokine expression after treatment with viral proteins Tat or glycoprotein 120 (gp120) with/without morphine. Murine …
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The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation.
… study was to investigate the distribution of opiates (heroin specific compounds) and cocaine and their respective metabolites in VH and muscle with a view to elucidating the interpretive value of these tissues. Analytical methods were developed and validated to measure drug concentrations in …
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Opiate Regulation of Lordosis: Neurochemical Evaluation of the Role of Opiate-Serotonergic Interactions
<p>Opiates are important regulators of reproductive function in the rat, potently inhibiting gonadotropin secretion. However, the role of opiates in the control of lordosis, hormone-dependent female sexual behavior, is less clear. While opiate agonists inhibit lordosis, antagonists do not …
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Qualitative Reports Of Michigan Medical Marijuana
… they reduced overall drug use, especially opiates, by using medical marijuana. Patients and caregivers also claimed medical marijuana was preferred over opiates, eased withdrawal from opiates, and in some cases was perceived as more effective at relieving pain. Other issues explored …
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The Role of Adult Hippocampal Neurogenesis in Morphine Addiction
… the relationship between self-administered opiates and adult DG neurogenesis remains unexplored. This dissertation investigates both the role of adult DG neurogenesis in morphine-related behaviors and the effects of self-administered opiates (morphine and heroin) on adult DG neurogenesis. I …
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The Role of Adult Hippocampal Neurogenesis in Morphine Addiction
… the relationship between self-administered opiates and adult DG neurogenesis remains unexplored. This dissertation investigates both the role of adult DG neurogenesis in morphine-related behaviors and the effects of self-administered opiates (morphine and heroin) on adult DG neurogenesis. I …
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Development and partial validation of a method for the quantification of benzodiazepines and antidepressants in whole blood, serum and urine by liquid chromotography - Tandem mass spectrometry
… method for certain benzodiazepines, opiates and antidepressants in whole blood, serum and urine by LC-MS/M5 and to consequently validate the analytical method for official use in the Division of Pharmacology at the University of Cape Town.
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Sleep apnoea and cardiac surgery: Screening, prevalence and postoperative outcomes
… population is unknown but deleterious effects of opiates/opioids, common pain relieve medication following surgery have previously been proposed. There is a move towards pre-operative screening for OSA prior to surgery but the best screening methodology has not yet been established and more …
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Modeling HIV-1 Infection and Immune Responses Under Drugs of Abuse
… is a major concern. Drugs of abuse, such as opiates, have been widely associated with enhanc ing HIV replication, accelerating disease progression, and diminishing host-immune responses. Moreover, opiates such as morphine have also been associated with de creasing the viral mutation rate. The …
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Evaluation of the impact of the New Jersey Access Initiative mentorship program on drug using behavior in clients with opiate dependence
… were 2,424 individuals were addicted to opiates. Results indicated that none of the participants reported receiving mentoring services. In addition, large amounts of incomplete and missing data in the dataset made statistical analyses impossible. Instead, descriptive results on drug …
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Experiences and satisfaction with methadone maintenance treatment (MMT) health services: views from a small Ontario city
Addiction to opiates is a complex public health issue affecting thousands of Canadians. Methadone Maintenance Treatment (MMT) is considered the gold standard in Canada, and the world, for treating opiate dependence. In the past, Canadian research into opiate addiction and the effectiveness of MMT …
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Adolescent Involvement in Alcohol and Drug Use
… amphetamines, barbiturates, cocaine, the opiates and also the hundreds of medicines to be found in chemist shops. Our society is a drug taking society, that is a pill for every ill. There are drugs for sleeping, headaches, stomach ailments, almost everything really. When young children see …
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The detection of drugs of abuse in biological matrices using enzyme-linked immunosorbent assay and liquid chromatography-tandem mass spectrometry
… method showed good correlation results for opiates compared to the GC-MS method. 6-MAM was however detected in more root segments and segments excluding roots by LC-MS-MS. Morphine was detected in a greater number of root segments by LC-MS-MS compared to GC-MS. However, morphine was detected …
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Standardized post-anesthesia handoff to improve interdepartmental communication
… anesthetic gases and medications while opiates and regional medications are onsetting. During this period, the patient also has an increased need for supplemental oxygen. This quality improvement project attempts to observe if the standardization of handoff between the CRNAs and PACU RNs …
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Enantiodivergent chemoenzymatic synthesis of codeine
… for the transformation of naturally occurring opiates into medicinally relevant derivatives. Two studies on the conversion of thebaine into the commercially available analgesic hydrocodone, two novel ·transition metal catalyzed N-demethylation procedures for opioids, and the development of a …
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Perceived relationship quality as a predictor of women's dropout from substance abuse treatment
… their partners. The primary drugs of choice were opiates, alcohol, and cocaine. Relationship perceptions were assessed prior to treatment by using the Kansas Marital Satisfaction Scale, the Dyadic Formation Inventory, and the Family Assessment Device. These scales all measure relationship quality …
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HEALTH EQUITY IN PAIN MANAGMENT DURING THE OPIOID EPIDEMIC: HOW STEREOTYPES, RACISM, BIAS HARM VULNERABLE POPULATIONS
… distribution of pain medication, especially opiates. The way to do this is through conversation and discussions around systemic racism and implicit bias. These can take the form of rounds or group discussions within a healthcare setting. There are many ways to combat this bias, but among the …
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