Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 51 for “"Oocyte Maturation"”.
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Paxillin is a Novel Regulator of Xenopus Oocyte Maturation
Oocyte maturation is triggered by steroids in a transcription-independent fashion that involves an unusual positive feedback loop whereby MOS (a germ cell specific Raf) activates MEK1, which in turn activates ERK2. ERK2 then acts back on MOS to enhance its expression resulting in amplification of …
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EGFR Signaling Is Necessary for Gonadotropin-Induced Steroidogenesis and Oocyte Maturation
… female fertility, including steroidogenesis, oocyte maturation, and subsequent ovulation. Studies were designed to examine the LH-induced signaling pathways that regulate ovarian steroidogenesis, as well as the subsequent role of steroids and their receptors on oocyte and follicle development. …
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MicroRNA expression and function during porcine oocyte maturation and early embryonic development
<p>Understanding oocyte maturation and embryo development in the pig is essential to improving farm animal reproduction efficiency. Many reproductive tissues are associated with a high degree of transcriptional and translational turnover that may be in part regulated by non-coding RNA such as …
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Regulatory mechanisms in cumulus expansion, oocyte maturation and block to polyspermy in mammals
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The oocyte-to-embryo transition : regulation of oocyte maturation and egg activation in Drosophila
… be highly regulated to ensure that growth of the oocyte and chromosomal segregation are coordinated properly. To do this, meiosis arrests at two points to permit oocyte differentiation and coordination with fertilization. In Drosophila, the first arrest in prophase I is released by oocyte …
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Role of Xenopus p21-activated kinase 2 (X-PAK2) in polar body formation during oocyte maturation
Vertebrate oocytes are physiologically arrested in meiotic prophase until shortly before ovulation. Under the influence of gonadotropic hormones, these oocytes resume meiosis and progress to metaphase II, in which they await fertilization. The transition from prophase to metaphase II is termed …
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Mouse Oocyte Maturation and Embryo Development After Exposure to Vemurafenib (PLX4032), an Anti-Melanoma B-RAF V600E Inhibitor
… also inhibits the wild type B- and C-Raf. In oocyte maturation, the C-Raf/MAPK pathway acts as an important self-enhancing and promoting system, w hereas in embryo development, the C-Raf/M APK pathway participates in pre- and post- implantation embryo proliferation and differentiation.</p> …
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Gene expression and human oocyte maturation: transcriptional control and post-transcriptional mechanisms based on intercellular signalling via exosomal miRNAs in follicular microenvironment
Lo scopo di questa tesi è la caratterizzazione dei profili di espressione di mRNA e miRNA nel gamete femminile e nel suo microambiente, rispettivamente, in condizioni fisiologiche e non, al fine di i) valutare l'effetto della vitrificazione sul profilo biomolecolare degli ovociti, ii) comprendere …
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In vitro maturation and fertilization of porcine oocytes and evaluation of male fertility
… incubation systems for in vitro porcine maturation and for in vitro fertilization (IVF), and utilizing these in vitro matured oocytes and in vitro fertilization techniques to determine the difference of sperm fertility from different boars. In the study of in vitro oocyte maturation, the …
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Uncovering a fundamental mechanism underlying female oocyte quality and RASopathies using C. elegans as a model system
… <p>The RAS/ERK signaling pathway regulates oocyte development and maturation across species. In <em>Caenorhabditis elegans</em> (<em>C. elegans</em>), ERK activity switches between sustained activation during oocyte formation and inactivation during oocyte maturation, fertilization, and …
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G Protein and Androgen Signaling in Ovarian Function
Oocytes are held in meiotic arrest in prophase I until ovulation when gonadotropins trigger a subpopulation of oocytes to resume meiosis in a process termed "maturation." Meiotic arrest is maintained through a mechanism whereby constitutive cAMP production exceeds phosphodiesterase-mediated …
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The impact of GnRH-agonist triggers on autologous in vitro fertilization outcomes: A retrospective analysis
… stimulation with exogenous gonadotrophins and oocyte maturation before ultrasound guided aspiration. GnRH-agonists have been utilized as an alternative to hCG for oocyte maturation prior to follicle aspiration. GnRH-agonist triggers are proven to lower ovarian hyperstimulation syndrome risk, a …
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Oxidative stress mechanisms within the developing porcine oocyte and the effects of antioxidant supplementation
… stress contributes to inadequate in vitro maturation of porcine oocytes which leads to a failure of successful fertilization and embryo development. Therefore, the overall objective of this research was to characterize the mechanisms of oxidative stress in maturing oocytes and determine how …
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Role Of Maternal Sin3a In Reprogramming Gene Expression During Mouse Preimplantation Development
… from our lab of oligo (dT) primed mouse oocyte and 1-cell embryo cDNA revealed an elevation in the relative abundance of the Sin3a transcript between the oocyte and 1-cell stages; the elevation in relative transcript abundance suggests that the Sin3a transcript undergoes translational …
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DISSECTING THE ROLE OF REACTIVE OXYGEN SPECIES IN EARLY MAMMALIAN EMBRYOGENESIS
… impairing embryo quality during the processes of oocyte maturation, fertilization, and early embryonic development in vitro. However, ROS also play essential roles as regulators of physiological processes, leading to the widely accepted hypothesis that excessive suppression of ROS could negatively …
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MATERNAL DETERMINANTS OF OOCYTE AND EMBRYO QUALITY
Oocyte quality plays a critical role in establishment of pregnancies, embryo development, implantation and the health of offspring. The oocyte provides maternal factors necessary for the initial development of its embryo during the period of transcriptional silence. Despite the consistent increase …
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IN VITRO EMBRYO PRODUCTION IN WOOD BISON (Bison bison athabascae)
… efficient protocols for collecting competent oocytes and to produce disease-free wood bison embryos by in vitro fertilization and culture. In Chapter 3, the in vivo and in vitro maturational characteristics of cumulus-oocyte complexes (COC) collected from live wood bison during the anovulatory …
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Factors affecting the quality and function of the bovine periovulatory follicle
… (specifically, follicle fluid) surrounding the oocyte during the maturation phase affects the ability of the cumulus-oocyte complex to progress through early embryonic development, and to investigate the relative effects of estradiol and progesterone on oocyte maturation and early embryo …
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Role of GnIH and GnRH in Paracrine Control of Gametogenesis in Zebrafish (Danio rerio)
… hormone (GTH)-induced spermatogenesis and final oocyte maturation in zebrafish, in vitro. The findings highlight the presence of GnIH and GnRH gonadal peptides and their receptors in zebrafish (Danio rerio) and provide strong evidence for direct actions of these hormones at the level of gonads. …
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