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Showing 1 to 1 of 1 for “"One pot aldol-Tishchenko reaction for the synthesis of 1,3-amino alcohol derivatives"”.
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Studies in asymmetric synthesis I the asymmetric alpha-alkylation of N,N-dimethylhydrazones II the synthesis of 1,3-amino alcohols via the aldol-Tishchenko reaction
Part I A large number of optically active drugs and natural products contain α- functionalised ketones or simple derivatives thereof. Furthermore, chiral α- alkylated ketones are useful synthons and have found widespread use in total synthesis. The asymmetric alkylation of ketones represents one of …