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Showing 1 to 3 of 3 for “"Oncogene Proteins, Fusion"”.

  1. Investigating the Functional Contributions and Tumorigenic Potential of Cancer/Testis Antigens and Their Interacting Partners

    The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.

    utswmed Repository record for Investigating the Functional Contributions and Tumorigenic Potential of Cancer/Testis Antigens and Their Interacting Partners (opens in a new tab)

  2. Identifying CDK8/19 as a Novel Regulator of EWS-FLI1 Function in Ewing Sarcoma

    Ewing sarcoma, a pediatric bone cancer, is characterized by the translocation of the Low Complexity (LC) domain from an RNA binding protein (EWSR1, FUS, or TAF15) with the DNA binding domain of an ETS transcription factor. The translocation EWS-FLI1 accounts for 90% of Ewing sarcoma tumors and a …

    utswmed Repository record for Identifying CDK8/19 as a Novel Regulator of EWS-FLI1 Function in Ewing Sarcoma (opens in a new tab)

  3. Identification of EWS-FLI1 Regions Necessary for Ewing Sarcoma Proliferation

    Ewing sarcoma is pediatric bone malignancy defined by a translocation between EWS and ETS family transcription factor. EWS-FLI1 (EF) is the most common translocation and codes for a novel transcription factor that combines the N-terminus of EWS, which contains LC domain comprised of tyrosine rich …

    utswmed Repository record for Identification of EWS-FLI1 Regions Necessary for Ewing Sarcoma Proliferation (opens in a new tab)