Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Omicron variant"”.
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Disruption and The Space Between: Staging The Tao of the World in Precarious Times
… this piece with a specific focus on: (1) how the Omicron variant of COVID-19 affected the rehearsal process; (2) the role of disruption as a tool to challenge assumptions and prompt creative thinking; and (3) the liminal space between Asian and Western cultures and between logical and creative …
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Computational Analysis of Antibody Binding Mechanisms to the Omicron RBD of SARS-CoV-2 Spike Protein: Identification of Epitopes and Hotspots for Developing Effective Therapeutic Strategies
<p>The advent of the Omicron strain of SARS-CoV-2 has elicited apprehension regarding its potential influence on the effectiveness of current vaccines and antibody treatments. The present investigation involved the implementation of mutational scanning analyses to examine the impact of Omicron …
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Computational Study of Vaccination Strategies to Change B Cell Immunodominance
… a third dose of SARS-CoV-2 vaccines against the Omicron variant. Through computational models and human vaccination data, we find that a third dose significantly boosts neutralizing antibody responses by targeting less-mutated, subdominant epitopes. This is facilitated by pre-existing antibodies …
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Aptamers that bind SARS-CoV-2 spike protein for COVID-19 rapid diagnostics and therapeutics
… One hurdle is the emergence of SARS-CoV-2 variants of concern, including the Omicron variant, which has enhanced infectivity and immune invasion. Improved rapid tests can limit viral spread by informing individuals of their infection status for personal risk assessment as well as disease …
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Virus from the Global South: A comparative analysis on Twitter commentary on China x Covid-19, and South Africa x Omicron
… Nearly two years later, in November 2021, variant B.1.1.529 was discovered in South Africa. This variant was named Omicron and is considered a variant of concern by the WHO. In response, various countries from the Global North initiated travel bans for several southern African countries. …
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EPIDEMIOLOGIA GENOMICA DELLE PRINCIPALI VARIANTI DI SARS-COV-2 CIRCOLANTI IN ITALIA PRIMA E DURANTE L'ERA OMICRON
GENOMIC EPIDEMIOLOGY OF THE MAIN VARIANTS OF SARS-CoV-2 CIRCULATING IN ITALY BEFORE AND DURING THE OMICRON ERA Introduction Since the beginning of the pandemic, SARS-CoV-2 has shown a great genomic variability, resulting in the continuous emergence of new variants that has made their global …
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CHARACTERIZATION OF THE INTERACTION BETWEEN HEPARAN SULFATE AND THE SPIKE (S) PROTEIN OF THE LATEST SARS-COV-2 VARIANTS
… events differs in the latest and most widespread variants of SARS-CoV-2, through the application of complementary computational and experimental approaches that combine NMR spectroscopy and different computational tools. We have selected two hexasaccharides as HS mimetics to probe their …
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Using proxy markers from routine diagnostic PCR testing to assess the disease severity of new SARS-CoV-2 variants
Background With the emergence of new SARS-CoV-2 variants, understanding the clinical implications of these variants in our South African setting is critical. The Delta variant (B.1.617.2) has been associated with more severe disease, but most of this data is from high income countries. And while …
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From Entry to Dysfunction: SARS-CoV-2 Neuropathogenesis in Peripheral Sensory and Autonomic Neurons and Its Implications
… As the COVID-19 pandemic progressed, numerous variants of SARS-CoV-2 emerged, calling into question the impact of viral variants on the neuroinvasive potential of these variants relative to ancestral SARS-CoV-2. This dissertation further shows, using SARS-CoV-2 XBB1.5, a contemporary Omicron …