Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Oligosaccharide synthesis"”.
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Fluorous assisted one-pot oligosaccharide synthesis and chemical synthesis of homogeneous heparan sulfate proteoglycan
… method for synthesizing bioloigically important oligosaccharides. Chapter 1 summarized the progress in this area in recent years. This approach has unique characteristics compared to traditional oligosaccharide synthetic methods. This chapter discussed its chemoselectivity and stereoselectivity …
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I. Chemoselective Dehydrative Glycosylation With Application Toward Oligosaccharide Synthesis. II. Sulfide-Mediated Direct Glycosylation of C(1)-Hydroxyl Glycosyl Donors. III. Studies Toward the Total Synthesis of Auriside A
… development of novel strategies for the total synthesis of auriside A are present in the third part of the dissertation. The hemiacetal disaccharide portion of auriside A is successfully synthesized. The convergent synthesis of the auriside aglycon component is accomplished in 17 linear steps …
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Automated synthesis of the Lewis blood group oligosaccharides
… are markers of specific cell types. These oligosaccharides are involved in recognition, adhesion, and signal transduction events. Advances in molecular glycobiology rely heavily on straightforward access to structurally defined oligosaccharides, but traditional syntheses of complex …
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Synthesis and Antifungal Evaluation of Spirostane Saponins
… have been prepared which could be used for the synthesis of</p> <p>various saponin derivatives in order to discover novel saponin based antifungal agent.</p> <p>Various mono and disaccharide derivatives of these steroids have been synthesized and</p> <p>evaluated for their antifungal activity …
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Development of Mono-de-N-acetylated β-(1→6)-N-acetyl-D-glucosamine Substrates for Characterization of PgaB Hydrolase Activity
… biosynthetic machinery is responsible for the synthesis and export of dPNAG in Gram-negative bacteria. PgaB is a two-domain periplasmic protein that processes PNAG prior to its export to the extracellular space. ΔpgaB strains have an impaired biofilm-forming phenotype, making PgaB a potential …
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Toward the Synthesis of CAY-1, an Antifungal Steroidal Saponin
… up to 100 ìg/mL. The development of a practical synthesis of CAY-1 will potentially allow for further exploration of its medicinal utility and provide the opportunity to synthesize derivatives of CAY-1 which could be investigated in structure-activity relationship studies. To this end, methods …