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Showing 1 to 20 of 30 for “"Oligopeptides"”.
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Synthesis and mass spectrometry studies of oligopeptides
… the effect of chirality on intrinsic acidity of oligopeptides. Gas-phase acidity (Δ<sub>acid</sub>G) and related thermochemical parameters (Δ<sub>acid</sub>H, and Δ<sub>acid</sub>S), of model N- and C-terminal cysteine polyalanine peptides in which one L-alanine was substituted by a D-alanine …
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Applications of Oligopeptides and Liquid Crystals for Chemical Sensing
… specificity, in Chapter 4 and 5, we identified oligopeptides that specifically bind to thiacloprid, imidacloprid, and glyphosate by using phage display screening, and we integrated the oligopeptides in SPR biosensors for detecting such molecules. In Chapter 6, we combined LC and oligopeptide to …
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Establishment of gas-phase thermochemical values of various small organic compounds and oligopeptides
… molecular systems: small organic molecules and oligopeptides. The gas-phase acidities were measured and the structures of the molecular species were calculated. The small molecules investigated included methylparaben, ibuprofen, and triclosan, all known to have some biological activity. The …
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The variation of the gas phase acidity of a cysteine residue in oligopeptides
<p>The altered acidities of amino acid residues in folded proteins can be used as a good indication for the diverse functions, stabilities as well as folding-unfolding states of the proteins. Previously, our group has investigated the gas phase acidities of a series of cysteine containing peptides …
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Part1. Relative antioxidant efficiency of synthetic and natural compounds; Part 2. Synthesis, characterization of cysteine oligopeptides and assessment of their antioxidant activity
… of cysteine containing hydrophobic oligopeptides. Two types of oligopeptides L-cysteine homo-oligopeptides and L-cysteine, L-methionine hetero-oligopeptides were synthesized through papain catalyzed oligomerization reactions."--Abstract, page iii.
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Microfluidic-based continuous self-assembly, alignment, and printing of oligopeptides with π-conjugated cores accompanied by advanced single molecule characterization
Organic semiconducting materials exist in an immense and complex space that,despite decades of extensive exploration, still has unexplored regions with exciting potential. The mysteries of this science lie in the myriad combinations in which organic building blocks can be arranged and how these …
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Synthesis and evaluation of vegetable (soybean) oil based epoxy resin for beverage can coating and enzymatic synthesis and characterization of tailored N&C end protected oligopeptides
… characterization of tailored N & C end protected oligopeptides. Supplementation of limiting amino acids plays an indispensable role in improving the feed efficiency in animal production. However, direct supplementation with crystalline amino acids has been found to be inefficient due to extensive …
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Thermochemical differences in lysine and lysine-homolog containing oligopeptides: Determination of basicity and gas-phase structure through mass spectrometry, infrared spectroscopy, and computational chemistry
<p>The data presented in this thesis is a comprehensive study on the nature of peptide structure and how subtle and systematic changes in sequence and sidechain affect the basicity, ion stability, and conformation of a peptide. The peptides characterized were acetylated polyalanine di-, tri-, and …
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Studio di biomateriali usati come scaffold per Tissue Engineering e loro caratterizzazione con tecniche spettroscopiche vibrazionali e di analisi termica
… (PCL-HA), surface modification with synthetic oligopeptides that elicit the interaction with osteoblasts. The characterization of the PCL-PLLA composite underlined that the degradation started along PLLA fibres, which are more hydrophylic, and they serve as a guide for tissue regeneration. …
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Modulatable endosomalytic, intracellularly biodegradable vectors for gene delivery
… delivery, we have designed p\(K_a\) modulatable oligopeptides (2COPs) by combining with lysine, histidine and cysteine residues which will bind DNA extracellularly, internalize via endocytosis, provide a tunable endosomal release mechanism, and provide a degradable backbone in order that the DNA …
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Ligand design principles for perfecting stereoretention in Suzuki-Miyaura cross-coupling of unactivated CSP3 boronic acids
… the preparation of oligonucleotides and oligopeptides. However, small molecules possess greater structural diversity than these classes of macromolecules. The development of an iterative, building block-based synthetic strategy could nonetheless accelerate the discovery of new small …
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Recovery of Xylitol from Fermentation of Model Hemicellulose Hydrolysates Using Membrane Technology
… of the Lowry's method positive material (such as oligopeptides and peptides). Permeate from the 10,000 MWCO membrane was collected and crystallized. Crystals were analyzed by HPLC for xylitol and impurities and determined to have purity up to 90.3%.
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Soil Organic Nitrogen - Investigation of Soil Amino Acids and Proteinaceous Compounds
… the molecular orientation of self-assembled oligopeptides on mineral surfaces was investigated by employing synchrotron based polarization-dependent Near Edge X-ray Adsorption Fine Structure Spectroscopy (NEXAFS) techniques. Specific aims of this study were: 1) to assess potentially …
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Dimensionality reduction and multiscale modeling for the understanding of protein folding and hierarchical self-assembly
… the effects of environment and chemistry upon oligopeptides that spontaneously assemble into bioelectronic nanostructures. By employing coarse-grained molecular dynamics to reach sufficient length and time scales to observe salient properties of assembly, I demonstrate that aggregation proceeds …
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Mechanical behavior and microstructure of self-assembling oligopeptide gels
… One class of hydrogel is formed from synthetic oligopeptides that self-assemble into a solution of beta-sheet filaments. These filaments can aggregate to form a gel suitable for culture of various cell types. Examples of such self-assembling peptides are RAD16-I, RAD16-II, and KLD-12. One …
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A Promiscuous Path to Novel Guanidines: Arginine-Modifying Enzymes as Key Synthetic Players
… including arginine analogues, derivatives, and oligopeptides. The process relies on the promiscuous methyltransferase SznE (or an engineered variant thereof) to transfer a methyl or ethyl group, from S-adenosylmethionine (SAM) or S-adenosylethionine (SAE), respectively. The enzyme MtnN is …
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Synthesis and supramolecular assembly of biomimetic polymers
… approach to assemble highly aligned synthetic oligopeptides nanostructures using microscale extensional flows. This strategy enabled reproducible, reliable fabrication of aligned hierarchical constructs that do not form spontaneously in solution. In this way, fluidic-directed assembly of …
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Molecular thin films and their role in controlling interface properties
… solid phase peptide synthesis. Oligopeptides increased the magnitude of friction compared to a bare hydrophilic silicon wafer. Friction was a strong function of the nature of the monomer unit and was lower for hydrophilic films. There was a strong adhesion and therefore friction …
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Effects of copper on calcium metabolism and detoxification mechanisms in freshwater bivalve species of Anodonta
… is induced. Phytochelatins (PC) are Cys-rich oligopeptides synthesised by phytochelatin synthase from glutathione in plants and fungi. Phytochelatin synthase genes have recently been identified in invertebrates; this allows us to hypothesize a role of PC in metal detoxification in animals. In …
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Anticancer a-helical peptides and their structure / function relationships underpinning their interactions with tumour cell membranes
… and non-cancerous cell lines. In contrast to the oligopeptides from Mtaldon and Argos control dataset, C residues were observed to be completely absent from all 3 ACP subsets with an abundance of the positively charged K residues (relative frequency >0.3) in the ACPAO and ACPTpeptides. This …
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