Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Oligodendroglia"”.
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Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
… Exosomen. Wir zeigen, dass Exosomen der Oligodendroglia-Vorläufer Zelllinie Oli-neu and Exosomen von primären Oligodendrozyten effizient und selektiv von Mikroglia internalisiert werden, ohne eine proinflammatorische Reaktion hervorzurufen. Die Aufnahme der Exosomen erfolgt durch …
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Subcellular labelling of myelin protein (PLP and DM20) in the central nervous system
… two isoforms. The gene is expressed primarily by oligodendroglia of the central nervous system (CNS), with some expression (primarily of DM20) in the Schwann cells of the peripheral nervous system. In the CNS, the DM20 isoform is expressed initially prior to myelin initiation and expression …
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Cytoarchitectural Defects Secondary To Experimentally Induced Oligodendrocyte Death In The Adult And Developing Central Nervous System
… communication in which highly specialized oligodendroglia extend compacted spirals of cell membrane around individual axons of multiple neurons. Functionally similar to the insulation that encases household electrical wiring, myelin accelerates the conduction of electrical signals that …
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CNS Neural/Glial Progenitors as Targets of HIV-1 and Opiates: Effects on Proliferation and Population Dynamics May Alter Behavior Outcomes.
… cause pathology in neural progenitors and oligodendroglia (OLs) (Hauser et al. 2009). Thus, we have hypothesized that NPCs and/or glial progenitors may be targets of HIV proteins ± opiates drugs of abuse. To determine whether progenitors are targets of HIV-1, a multi-plex assay was …
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Mash1 Defines Lineage Restricted Neuronal and Oligodendrocytic Precursor Cells in Spinal Cord Development
Recent advances have defined distinct neural progenitor and early interneuron pools in the developing spinal cord and the molecular events that influence progenitor cell fate. However, these early neurons have not been traced to adult neuron types. The transcription factor Mash1 is transiently …
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Quantifizierung und zelluläre Lokalisation von Eisen in der Substantia nigra bei Patienten mit Parkinsonscher Erkrankung und gesunden Kontrollen
… verändert (KO: 4,31 mmol/l; PD: 4,11 mmol/l). • Oligodendroglia weisen in Abhängigkeit des verwendeten Zellmarkers unterschiedliche zelluläre Eisenkonzentrationen auf. Olig2-positive Zellen akkumulieren bei PD im Durchschnitt 250% mehr Eisen (KO: 2,76 mmol/l), CNPase-positive Oligodendrozyten ca. …
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Cohesin Promotes the Myelination Transcriptional Program in Oligodendrocytes
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Epigenetic Regulation of Oligodendrocyte Development and Regeneration in the Central Nervous System
Oligodendrocytes (OLs) produce myelin sheaths that electrically insulate axons and promote rapid propagation of action potentials in the CNS. The onset and timing of CNS myelination and remyelination requires precise coordination between epigenetic programming and transcriptional regulation. In …
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Behavioural, genetic and epigenetic determinants of white matter pathology in a new mouse model of chronic cerebral hypoperfusion
… distribution was studied in vitro in oligodendroglia cells at different stages of maturation, and interferon γ/ lypopolisaccharide activated and nonactivated microglia. The in vitro analysis demonstrated that 5hmC is high in OPC, activated and nonactivated microglia, but it is low in …
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Stab Wounds to Rat Brains : Demyelination, Remyelination and the Cellular Response, Particularly of Oligodendrocytes
… between 28 and 60 dpo. At the same time, no oligodendroglial reaction was shown on the contralateral side. In the serial sections, GFAP+ astrocytes were detected on both sides of the brain. These GFAP+ astrocytes were different from reactive MOSP+ oligodendrocytes in terms of cell shape, …