Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 51 for “"Oestradiol"”.
-
The effects of oestradiol administration on energy metabolism during prolonged exercise in amenorrheic athletes
… to prolong muscle glycogen depletion. Oestradiol (the female sex hormone) has been shown to increase muscle glycogen content at rest and increase the availability of fats as a fuel source during exercise therefore delaying the onset of fatigue. The effects of oestradiol administration …
-
Biochemical studies on Oestradiol 17β in human mammary tumours and chemically induced rat mammary tumours
… retention of administered tritium labelled oestradiol 170 by certain mammary tumours is due to the possession of specific oestradiol binding components similar to those occurring in normal oestrogen target tissues such as uterus. The possession of such components may be related to the …
-
Control of LH secretion in red deer (Cervus elaphus)
… series of studies which examined the effects of oestradiol, progesterone, and season on the pulsatile secretion of LH in red deer (Cervus elaphus). In the first experiment two groups of long-term ovariectomized hinds (n=10, with and without intravaginal progesterone pre-treatment) were injected …
-
Regulation of LH in the female common brushtail possum (Trichosurus vulpecula)
… and the seasonal change of LH in response to oestradiol in the possum through the development of two main hypotheses. The first hypothesis proposed that LH is secreted in pulses from the anterior pituitary gland in response to discrete pulses of GnRH released from the hypothalamus, both of …
-
Investigation into the Vasomotor Signs and Symptoms of the Menopause
… rest and during heat induced vasodilatation. 17B-oestradiol appeared to affect the responsiveness of both vascular and non-vascular sympathetically innervated smooth muscle. 178- oestradiol depressed the responses of the rat isolated vas deferens to transmural stimulation to noradrenaline and to …
-
Neuroendocrine Mechanisms Involved in the Control of Ovarian Development and Vitellogenesis in the Rainbow Trout
… were used to determine serum levels of oestrone, oestradiol-17B, testosterone, vitellogenin and calcium and these correlated with histological data both during the reproductive cycle and after treatment with hormones. Single and double injections of oestradiol-17B respectively produced primary and …
-
The Influence of Ovarian Sex Steroids on Insulin Receptor Status in Mice
… nor the 2 week oral administration of oestradiol (5 ug/kg/day) to ovariectomised mice had any significant effect on the insulin binding capacity of hepatocytes in the presence of insulin concentrations ranging from 0 to 1000 ng/ml. The insulin binding capacity of hepatocytes was, …
-
A Comparison of Cultured Human Dermal Fibroblasts Derived from Terminal and Vellus Hair Bearing Skin. Differences in the expression of inhibitors of apoptosis proteins, oestrogen receptors, and responses to oestradiol under normal and wound induced conditions
… and caspase 3 activity in the presence of 17β-oestradiol and changes in mRNA expression of the oestrogen receptors (GPR30, ERα and ERβ) were compared between the two cell types. IAP protein expression was generally found higher during mid anagen of the hair cycle in murine skin and hair …
-
Studies on the influence of sex hormones on glucose tolerance and insulin secretion in the rat
… that treatment of ovariectomized females with oestradiol, progesterone and a preparation of gonadotrophins produces similar alterations of glucose metabolism and the circulating insulin pool. Evidence is presented that oestradiol and progesterone induce these changes within six hours, and that …
-
A study of the regulation of oestrogen receptor alpha by tissue factor in breast cancer cells
… activation. Furthermore, exogenous TF suppressed oestradiol-mediated cell proliferation through a pathway partly mediated through PAR2 activation, and also reversed the inhibitory influence of oestradiol on cell invasion. Exogenous TF also decreased the transcriptional activity of ERa via the …
-
The Implications of Wicked Problems for the Legitimacy of European Environmental Policy Development. The case of Environmental Risks from the Pharmaceutical Endocrine Disrupter, 17α-Ethinyl Oestradiol under the European Water Framework Directive
… endocrine disrupter 17 alpha-ethinyl oestradiol (EE2), which is an active ingredient in the contraceptive pill, confronts government responsibilities for citizens' health with potential environmental risks from its presence in aquatic ecosystems. Further to a risk appraisal process …
-
Study of the pharmacological modification of neuroendocrine mechanisms controlling ovulation in the rat.
… LH surge, which was restored by LHRH or oestradiol plus progesterone. Administration of oestradiol alone restored ovulation to only 43% of RMI 12,936-treated rats. The negative feedback effect of testosterone on LH release showed similar characteristics. Although RMI 12,936 was shown to …
-
Hormones and behaviour during the menstrual cycle
… ", and relate such changes to the sex steroids, Oestradiol, Progesterone and Androgens.
-
ΜΕΤΑΒΟΛΕΣ ΙΔΙΟΤΗΤΩΝ ΤΗΣ ΤΡΑΧΗΛΙΚΗΣ ΒΛΕΝΝΑΣ ΤΟΥ ΠΡΟΒΑΤΟΥ ΥΣΤΕΡΑ ΑΠΟ ΣΥΓΧΡΟΝΙΣΜΟ ΤΟΥ ΟΙΣΤΡΟΥ ΚΑΙ ΕΠΙΔΡΑΣΗ ΤΟΥΣ ΣΤΗ ΣΥΜΠΕΡΙΦΟΡΑ ΤΩΝ ΣΠΕΡΜΑΤΟΖΩΑΡΙΩΝ
… IN THE CONCENTRATIONS OF PROGESTERONE AND OESTRADIOL-17B IN BLOOD PLASMA.ON EVALUATION OF THE RELEVANT RESULTS IT WAS FOUND THAT: THE CHANGES IN THE CONCENTRATIONS OF OESTRADIOL-17B AND PROGESTERONE ARE RELATED TO THE PROPERTIES OF CERVICAL MUCUS, WHILE THE LATTER DETERMINE THE DEGREE OF …
-
Investigations into the sensing capabilities of an electrochemical immunosensor employing polyaniline as a mediator species
… towards developing real-time imrnunosensors to oestradiol and p60. This ork involved the synthesis of horseradish peroxidase (HRP) conjugates with oestradiol, and p60 or use in a competitive immunosensor, as well as immunoassay characterisation of the proteins, nd their application to the …
-
A study of the relationship of the internal endocrine environment to the p53 network, cyclin D1 and replication licensing proteins in breast cancer
… proteins, if any, with the change in serum oestradiol levels in pre-menopausal women, the postmenopausal women served as the control. The rest of the patients included had tissue samples and blood taken at one time point only i.e. at resectional surgey. Samples comprised formalin fixed …
-
Characterisation of oestrogenic properties of Isoflavones derived from Millettia griffoniana Baill.: - Molecular mode of action and tissue selectivity
… of Griff C in ovariectomised Wistar rats. 17β-oestradiol (E2: 10 µg/kg BW) was used as positive control. They were treated daily for three consecutive days and sacrificed 24 hours after receiving the last dose. The whole uterus was removed and weight. Liver and vena cava fragments were also …
-
Sex difference in the endocrine response of adult domestic chickens to gonadotrophin-releasing hormone-I
… cockerels in vitro after incubation with 176-oestradiol. The membrane fluidity of pituitary cells from laying hens was lower than that from adult cockerels and shown to be induced in pituitary cells from juvenile chickens by treatment with 17B-oestradiol. Attempts to establish an …
-
A study of the factors controlling embryo transport in the oviduct of the mouse.
… of this fluid is uncertain. Administration of oestradiol by injection into one bursa ovarica produces effects which are more pronounced than SC administration and are laterally biased. An in vitro system has been developed in which embryo transport occurs from Day 2 and Day 3 onward for up to …
-
Stimulus-Mitosis Coupling in the Rat Thymic Lymphocyte
… which is independent of magnesium ions. High oestradiol concentrations by further increasing intra— cellular calcium concentrations beyond a threshold inhibit this response...
Page 1 of 3