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Showing 1 to 2 of 2 for “"Oesophageal organoids"”.

  1. Exploring the role of BCL11A in the oesophagus and mammary gland using in vivo lineage tracing and 3D organoid models.

    … data suggest that it is also upregulated in oesophageal squamous carcinoma (OSCC). With proven roles in malignancy and little knowledge about its physiological function, this work reports the combined use of in vivo lineage tracing techniques and in vitro 3D organoids to explore the …

    cambridge Repository record for Exploring the role of BCL11A in the oesophagus and mammary gland using in vivo lineage tracing and 3D organoid models. (opens in a new tab)

  2. Clonal Dynamics in Barrett's Oesophagus and Oesophageal Adenocarcinoma

    Introduction Outcomes in oesophageal adenocarcinoma (OAC) are poor, largely driven by most patients being diagnosed at a late stage. OAC has a metaplastic pre-cursor lesion, Barrett’s oesophagus (BO), which can be monitored and effectively treated if dysplasia develops. Screening for BO could …

    cambridge Repository record for Clonal Dynamics in Barrett's Oesophagus and Oesophageal Adenocarcinoma (opens in a new tab)