Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Ocular hypertension"”.
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Drug delivery strategies to overcome ocular hypertension
Glaucoma, a group of ocular diseases that cause optic nerve damage and vision loss, is the second leading cause of irreversible blindness worldwide. Current treatments, primarily eye drops, require frequent administration due to natural tear fluid turnover and blinking, which reduces patient …
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Perioperative Administration of Topical Dorzolamide Hydrochloride/Timolol Maleate Reduces Postoperative Ocular Hypertension in Dogs Undergoing Cataract Surgery
Development of cataracts is a relatively frequent ocular disease of the dog and cataract extraction via phacoemulsification (PE) is commonly performed by veterinary ophthalmologists. Postoperative ocular hypertension (POH) describes the elevation of pressures within the eye during the acute …
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Identification of Actin Binding Proteins Associated with Cross-Linked Actin Networks
… 122 titles. Glucocorticoid therapy can leady to ocular hypertension and glaucoma. The purpose of this study is to examine mechanisms contributing to increased intraocular pressure using tissue culture models of steroid-induced ocular hypertension through identification of specific actin-binding …
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Selenium Effects on the Trabecular Meshwork
… selenium supplementation may increase risk for ocular hypertension and glaucoma. The purpose of this project was to determine the effects of selenium on the conventional "trabecular" aqueous outflow pathway, a likely site of pathology for glaucoma. Human trabecular meshwork (HTM) cells and human …
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Η ΣΥΧΝΟΤΗΤΑ ΤΗΣ ΨΕΥΔΟΑΠΟΦΟΛΙΔΩΣΗΣ ΣΤΗΝ ΗΠΕΙΡΟ
… BY THE DEPOSITION OF GREY FLAKES ON VARIOUS INTRAOCULAR STRUCTURES ESPECIALLY AT THE ANTERIOR SEGMENT. LINDBERG IN 1917 HASFIRST DESCRIBED THE CONDITION. IT IS FOUND TO OCCUR MORE COMMONLY IN SCANDINAVIA, RUSSIA, SOUTH AFRICA, GREECE ET.AL. THE NATURE AND MODE OF INHERITANCE OF EXFOLIATION REMAINS …
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Improving Compliance via Education, Reminders, and Evaluating Physician-Patient Concerns in Glaucoma
… diagnosed with primary open angle glaucoma or ocular hypertension at a single academic center (92 male and 102 female) and 16 glaucoma specialists volunteered their responses. METHODS: All 194 eligible patients were interviewed regarding glaucoma knowledge, medication usage, concerns, and …
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Advanced glycation end products as a biomarker for accelerated ocular ageing and glaucoma
… healthy participants and patients diagnosed with ocular hypertension (OHT), early stage normal-tension glaucoma (NTG) and early stage primary open angle glaucoma (POAG). A UK-specific food frequency questionnaire (FFQ) was developed and found to reliable and valid. This newly designed FFQ was …
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A pilot study to assess the feasibility of using the Travalert® dosing aid to measure adherence
… patients prescribed travoprost for glaucoma or ocular hypertension, were approached and stratified by phase of travoprost use: newly prescribed or follow-up. At baseline, self-reported adherence to travoprost was obtained from follow-up participants using questionnaires (Morisky Medication …
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The Relationship of Trabecular Meshwork Stiffness and Outflow Function
… of aqueous humor of the eye and setting intraocular pressure (IOP). TM dysfunction may lead to ocular hypertension which is the major risk factor in glaucoma. Although the outflow properties of the TM have been assessed over the last sixty years, very little work has been done assessing its …
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Magnetic Steering to Save Sight: Trabecular Meshwork Cell Therapy as a Treatment for Primary Open Angle Glaucoma
… The major risk factor for POAG is high intraocular pressure (IOP). Current clinical treatments for POAG aim to reduce IOP, but they often have low success rates. The trabecular meshwork (TM) is a key regulator of IOP and has been shown to undergo significant changes in POAG including a loss …
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Phenotypic Characterization of Segmental Human Trabecular Meshwork Cells
… TM cells towards a healthier phenotype to lower ocular hypertension.
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A study of the role of advanced technologies in glaucoma case-finding
… than 95% of referrals for suspected glaucoma and ocular hypertension. Case--‐ detection of glaucoma may be improved by using screening tests with better diagnostic accuracy, but standardised protocols for advanced technologies used alone, or in combination, to detect glaucoma are lacking. Chapter …
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Determining Mechanisms by which Pathological Extracellular Matrix induces Ocular Hypertensive Phenotypes in Human Trabecular Meshwork Cells
… meshwork (TM), it is implicated in elevated intraocular pressure (IOP), the only treatable risk factor for glaucoma. Herein, two different glaucoma-relevant cell-derived matrices (CDMs) were used to dissect the specific mechanisms by which diseased ECMs may precipitate ocular hypertensive …
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Chronic Ocular Hypertensive Model using Microbead Injection in Rats: Comparison of Polyurethane, Polymethylmethacrylate, and Polystyrene
Purpose: To establish and assess an ocular hypertensive rat model using intracameral injection with various microbeads of different sizes and materials. Methods: Chronic elevation of intraocular pressure (IOP) was induced by injection of various microbeads into the anterior chamber of …