Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Oct-2"”.
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Old protein, new perspective : the role of Oct-1 during embryonic development and lymphopoiesis
… acting elements with trans acting factors. The octamer element (5'ATGCAAAT-3') is conserved in Ig promoters and enhancers and is thought to be important in transcriptional regulation. To date, only two octamer-binding proteins have been identified in B cells, the ubiquitously expressed Oct-1 and …
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Luminescent Iridium(III) Cyclometalated Complexes: Host-Guest Chemistry and Application as Sensors
… Bu=n-butylamine, (Ir-CH2NH-Bu); R=CH2NH-Oct, Oct=n-octylamine (Ir-CH2NH-Oct); and R=CH2N-(Oct)2 (Ir-CH2N-(Oct)2). Chapter 2 demonstrated that the R group in the iridium(III) complexes significantly affects the photophysical properties. Luminescence and electrochemical studies confirmed …
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The Dual Role of OCA-B in B Cell Development and Signaling
<p>OCA-B (Oct coactivator from B cells) is a B-cell specific coactivator of transcription that acts in conjunction with the ubiquitously expressed activator, OCT-1 or the B cell-restricted OCT-2. OCT-1 or OCT-2 can bind an upstream octamer element with the consensus sequence 5'-ATGCAAAT-3' in …
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Synthesis And Evaluation Of Novel Tropane Compounds As Potential Therapeutics For Drug Abuse
… (Prozac). A series of 8-azabicyclo[3.2.1]oct-2-ene derivatives were synthesized from 3-tropinone based on the structure of triple re-uptake inhibitor, DOV 216, 303. The compounds were designed as potential triple re-uptake inhibitors which could exhibit equipotent affinities at the …
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Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex
… The transcription factors Bright, E2F1 and Oct-2 were found to bind both sequences in vitro and in vivo, opening up a possibility of mediating a link between the oriPI and the Cp. The binding sites of all three proteins were mapped to a short segment of Cp in close proximity of each other. …
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Poly(LA-co-TMCC)-graft-PEG Self-assembled Polymeric Nanoparticles for Targeted Drug Delivery
… P(LA-co-TMCC), was first synthesized by Sn(Oct)2 catalyzed bulk polymerization. In order to obtain the polymer product with a better-defined composition, the polymer synthesis was improved by using organo-catalytic ring-opening copolymerization. The copolymer molar mass and composition were …
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Structural and functional imaging of the human and small animal eyes using ultrahigh speed Fourier domain optical coherence tomography
Optical coherence tomography (OCT) is a non-invasive optical imaging technique that allows the three-dimensional structure of biological tissue to be visualized with micrometer resolution. In ophthalmology OCT has the unique advantage that it provides cross-sectional images of the retina and …
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Fundamental Studies of Various Poly(L-lactide)/clay Nanocomposite Systems by in-situ Polymerization
… When using tin (Il) 2-ethylhexanoate (Sn(Oct)2) as the catalyst, the reaction is believed to initiate from stannous alkoxides, formed from hydroxide (-OH) groups present in the reagents. Several quaternary ammoniums were ion-exchanged onto the surface of montmorillonite-Na+ in order to …
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Tandem reaction sequences on a zirconocene template
… core structures containing the cis-bicyclo[3.3.0]oct-2-ene skeleton. Zirconocene mediated co-cyclisation of 1,6-enynes provides unsaturated 5-membered zirconacycles which are homologated to 6-membered zirconacycles by insertion of 1,1-dihalo-1-lithio species (dihalogenocarbenoids). Further …
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Theoretical Studies of the Energies and Geometries of Strained Hydrocarbons
… III. Ab initio calculations on bicyclo (2.2.2) octa-2,5,7-triene (barrelene), bicyclo (2.2.2) octa-2,5-diene, bicyclo (2.2.2) oct-2-ene, and bicyclo (2.2.2) octane have been performed at the 3-21G, 6-31G* and 6-31G** SCF levels and at the 6-31G* RMP2 level and the contributions of zero-point …
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Approaches to the synthesis of azabullvalene
… successfully applied to cyclobutyl through cyclooctyl amines and described by us last year. Subsequently, by employing N -nitro so-N-bicyclo [4.1.0] heptyl ethyl carbamate, we have worked out the conditions for the generation of simple cyclopropyl azides and defined suitable reaction conditions …
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Structural characterisation and absolute stereochemistry of some degraded carotenoids from New Zealand honeys
… tramethylspiro[furan-2(3)H,7'[6']oxabicylco[3.2.1]oct[2']ene]-4'-one. Comparison of NMR-derived NOE and coupling constant data of kamahine A and B acetates with kamahine C acetate indicated the parent kamahines were C-4, C-5 epimers. The absolute configurations of the kamahines were determined by …
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Synthesis and Characterization of Functional Biodegradable Polyesters
… and catalyst/coinitiator systems based on Sn(Oct)2 afforded the preparation of star-shaped, poly(D,L-lactide)s (PDLLA)s of controlled molar mass, narrow molar mass distributions, and well-defined chain end functionality. Various modifications of star-shaped PDLLA resulted in macromolecules …
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Novel addition reactions of some benzopyrans
… -6H,8H-bis[1]benzopyrano[2,3-b:3.4'e]pyridin-6-yl]oct-2-en-4-ynonitrile. The 1,4-addition of dialkynylcuprates to chromone-3-carboxaldehyde afforded 2-ethynyl-3-hydroxymethylenechroman-4-ones which suffered acid catalysed rearrangement to Z-2-hydroxy-3-(2-propynylidene)chroman-4-ones. Several …
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Synthese und Charakterisierung von bioabbaubaren Polymeren auf der Basis von Polydepsipeptiden
… poly(ethylene oxide) with stannous octoate as a catalyst. of the resulting copolymers increases with increasing amount of morpholine-2,5-dione derivatives. No racemization of the isoleucine or leucine residue takes place during both homopolymerization and polymerization of …