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Showing 1 to 1 of 1 for “"OcrA ribosome protection"”.
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A Chemical-Genetic Map of Drug Resistance in Mycobacterium Tuberculosis
… led to the identification of a novel ribosomal protection protein, which we have termed OcrA, that confers resistance against ribosome inhibitors such as linezolid and chloramphenicol. This may allow for the rational engineering of linezolid analogs to avoid the activity of OcrA. The CRISPRi …