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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"OPG"”.
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Statins Regulate IL-1β - Induced RANKL and OPG Production by Human Gingival Fibroblasts
… by its soluble decoy receptor, osteoprotegerin (OPG), thus inhibiting osteoclast differentiation, activation and survival. RANKL and OPG are produced by many cells in the body including human gingival fibroblasts and PDL cells. At the moment, no data exist comparing the effect of statins on OPG/ …
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Die MMP9- und OPG-Expression von dermalen Fibroblasten und mesenchymalen Stammzellen nach Stimulation durch Myelom- und Hodgkinzelllinien
… reduced expression of the osteoprotective factor OPG by fibroblasts could be demonstrated after stimulation with conditioned mediums by the celllines U266 and IM9. Some matrix metalloproteinases seem to play an important role in the domain of angiogenesis of carcinomas, especially MMP9. The …
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RANKL and Osteoprotegerin Levels in Response to Orthodontic Forces
… for osteoclastogenesis, and osteoprotegerin (OPG) is a decoy ligand that competitively inhibits RANKL. A higher RANKL/OPG ratio is associated with areas of bone resorption, while a lower ratio occurs in areas of bone deposition and homeostasis. There have been almost no clinical studies of …
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Serum Osteoprotegerin, a Potential Novel Marker of Systemic Inflammation: The Influence of Obesity, Insulin Sensitivity and Oral Glucose Loading on its Circulating Concentrations
Circulating osteoprotegerin (OPG) promotes bone formation in vivo and correlates with the presence of type 2 diabetes, severity of vascular calcification and coronary artery disease. Obesity is a risk factor for diabetes and cardiovascular disease but little is known about the impact of body weight …
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Modulation of RANKL and Osteoprotegerin in Adolescents Using Orthodontic Forces
… for osteoclastogenesis, and osteoprotegerin (OPG) is a decoy ligand that competitively inhibits RANKL. A higher RANKL/OPG ratio is associated with areas of bone resorption, while a lower ratio occurs in areas of bone deposition and homeostasis. There has been almost no clinical study of RANKL …
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Osteoprotegerin: a pathological role in human abdominal aortic aneurysm
… receptor superfamily known as osteoprotegerin (OPG) is constitutively expressed within the human artery wall and, under pathological conditions, is upregulated and associated with vascular disease. Elaboration on the involvement OPG of in AAA will determine its potential as a pharmacological …
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Osteolyse beim Multiplen Myelom : Untersuchungen am Zellmodell
… and the soluble decoy receptor osteoprotegerin (OPG). Binding of RANKL to RANK leads to osteoclastogenesis and osteolysis whereas binding to OPG inactivates RANKL. Myeloma cells seem to disturb bone marrow microenvironment in a manner tipping the balance towards osteolysis. On one hand syndecan 1 …
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In vitro Differenzierung von Monozyten der Zelllinine RAW 264.7 zu Osteoklasten, deren Charakterisierung und Wechselwirkung mit Osteoblasten
Das RANKL/RANK/OPG-System spielt eine entscheidende Rolle in der Steuerung der Osteoklastendifferenzierung und -aktivierung durch Osteoblasten/ Knochenmarkbindegewebszellen im Rahmen des Knochenremodelings. Osteoblasten/Knochenmarkbindegewebszellen exprimieren RANKL. Dieses hat im Körper zwei …
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Muscular Strength Training Modifies Regulation of Bone Remodeling: Inferences From Serum Biomarkers in Young Women
… kappa-beta ligand (RANKL), osteoprotegerin (OPG), osteocalcin, and N-telopeptide (NTx) were measured in women aged 20 + 1.5 years (mean + SD) who underwent 32 weeks of unilateral isokinetic concentric or eccentric muscular strength training. Changes in serum biomarkers were compared with …
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Physical training, inflammation and bone integrity in elite female rowers
… bone (sclerostin (SOST), osteoprotegerin (OPG)), and receptor activator of nuclear factor kappa-B ligand (RANKL)) and energy metabolism (insulin-like growth factor-1 (IGF-1) and leptin), and inflammation (tumor necrosis factor-α (TNF-α)) in elite heavyweight female rowers. Blood samples …
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Automated Teeth Extraction and Dental Caries Detection in Panoramic X-ray
… methods, Panoramic or Orthopantomogram (OPG) images are commonly performed as the initial step toward assessment. OPG images are captured with a small dose of radiation and can depict the entire patient dentition in a single image. Dental caries can sometimes be hard to identify by …
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Vascular calcification as a risk factor for peripheral arterial disease and its effects on angiogenesis
… and 24-week-old mice, with high calcium levels (OPG(-/-)) and wildtype (C57BL6/J, control) mice. Blood flow reperfusion was assessed by Laser Doppler Perfusion Imaging (LDPI). In vitro, CM upregulated mRNA expression of calcification inductive genes, Bmp2 and Runx2. CM significantly decreased …
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Stress Conditioning and Heat Shock Protein Manipulation for Bone Tissue Engineering
… (OCN), osteopontin (OPN), osteoprotegerin (OPG), vascular endothelial growth factors (VEGF), and cyclooxygenase 2 (COX-2) mRNA at 8 hour post-heating (PH). The addition of GFs with heating induced OPG and VEGF genes more than heating or GF addition alone. OPN, OCN, and OPG secretions …
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THE ACUTE EFFECTS OF A SINGLE SESSION OF PLYOMETRIC EXERCISE ON MARKERS OF BONE TURNOVER IN BOYS AND MEN
… cross-linking telopeptide (NTx), osteoprotegrin (OPG) and receptor activator of nuclear factor kb ligand (RANKL). Boys had higher BAP levels at all time points, with an increase 24 hours post-exercise. No such increase was observed in men. Likewise, NTx levels were higher in boys, with a greater …
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Darstellbarkeit von Knochenstrukturen und enossalen Implantaten mit der Flächendetektor-Volumencomputertomographie und mit konventionellen radiologischen Verfahren - Ein Methodenvergleich
… intraoralem Zahnfilm (ZF), Orthopantomographie (OPG) und Digitaler Volumentomographie (DVT) verglichen. Ergebnisse: Bei der Erhebung der Daten waren die 3D-Verfahren den 2D-Verfahren aufgrund der überlagerungsfreien Darstellung deutlich überlegen. Die Implantate und periimplantären anatomischen …
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Genotipificação de amostras sorotipificáveis e não sorotipificáveis de Actinobacillus pleuropneumoniae através de RAPD
… 5b, 7, 11 e 12 isolados no Brasil. Os primers OPG e OPG-19, utilizados individualmente nas reações, foram mais adequados para a diferenciação dos sorotipos. O primer OPG-19 detectou polimorfismos semelhantes entrer os sorotipos 1, 3, 4, 5 e 11; e sorotipos 7 e 12. O perfil de RAPD detectado …
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Análise genética de características de resistência ao Haemonchus contortus em caprinos Crioulos
… perfis parasitológico (ovos por grama de fezes - OPG) e histológico (contagem de eosinófilos sanguíneos – EOSI; e volume globular - VG), para obtenção da resposta à resistência ao parasitismo Haemonchus contortus ao longo do tempo, oriundos de 138 caprinos da raça Crioula com idades variando de …
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Semiparametric Approaches for Dimension Reduction Through Gradient Descent on Manifold
… empirical cumulative distribution function. CS-OPG, a modified outer product gradient (OPG) method for CS, is developed as an initial estimator for CS-gemDR. The basis B of the CMS or CS is estimated by a gradient descent algorithm. An update scheme on a Grassmann manifold is to preserve the …
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Wirkungsweise von Bisphosphonaten auf die Expression verschiedener Knochenmarker in mesenchymalen Stammzellen der Plazenta
… Hochregulierung der mRNA-Expression von OPG und den klassischen osteoblastären Markern COL-I und AP. Die Kombination von ZOL und Vitamin D3 (VitD3) zeigte keine zusätzliche Steigerung der zu detektierenden mRNA-Expressionen. Durch die Zugabe von ZOL unter Kulturbedingungen der osteogenen …
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