"OMP decarboxylase" · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"OMP decarboxylase"”.

Biochemical Characterization of a Partial Deficiency for Ump Synthase in Holstein Cattle (Enzyme, Genetic Disorder, Metabolic Defect, Hereditary Orotic Aciduria)

Harden, Kathryn KnosherUniversity of Illinois at Urbana-Champaign2015

… of enzyme activity. The activities comprising UMP synthase, orotate phosphoribosyltransferase (OPRT) and orotidine-5'-monophosphate (OMP) decarboxylase (ODC) were measured separately. ODC activity was about 47% of normal in heterozygotes, comparable to the reduction in UMP synthase. …

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In search of catalytic proficiency: The importance of enzyme conformational change to orotidine 5’-monophosphate decarboxylase catalysis

Wood, Bryant M.University of Illinois at Urbana-Champaign2011

… biosynthesis, orotidine 5’-monophosphate decarboxylase (OMPDC). OMPDC catalyzes the decarboxylation of OMP to UMP; the uncatalyzed rate for this reaction has been estimated to be 2.8 x 1016 s-1 (1). The slow rate without OMPDC is attributable to the lack of internal stabilization of the …

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