Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"OIR"”.
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TWEAK/Fn14 Pathway is Activated by Hypoxia and is a Novel Mediator of Retinal Neovascularization
… used mouse model of oxygen-induced retinopathy (OIR), which is commonly used for studying NV. OIR was produced by maintaining C57BL/6 wild type neonatal mice in 75% oxygen from postnatal day (P)7 to P12 and room air from P12 to P17. Control mice were kept in room air (RA). Quantitative PCR showed …
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The traditionally protective cystathionine gamma-lyase/hydrogen sulfide pathway contributes to pathological retinal neovascularization in oxygen-induced retinopathy
… blotting was used to measure protein levels. OIR markedly upregulated CSE in wild type mice compared to age matched controls in room air. CSE+/- mice exposed to OIR showed significantly less vaso-obliteration and significantly more neovascularization compared to CSE-/- littermates (p<0.05). …
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Lokale Therapie der Sauerstoff-induzierten angioproliferativen Retinopathie im Mausmodell : Small Molecule Receptor Tyrosine Kinase Inhibitors
… angioproliferativen Retinopathie (OIR) im Mausmodell nach Smith zu untersuchen. Zum Einsatz kamen die drei Substanzen PTK787, MAE87 und MAZ186, die zur Gruppe der "small molecule receptor tyrosine kinase inhibitors" gehören. Das retinale Gefäßsystem wurde in Netzhautflachpräparaten …
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Evaluation Of HIF Inhibitors For The Treatment of Ocular Neovascular Diseases
… day (P) 12 in an oxygen-induced retinopathy (OIR) mouse model significantly reduced retinal neovascularization at P17. Administration of honokiol also prevents the oxygen-induced central retinal vaso-obliteration a characteristic feature of the OIR model. Honokiol also enhanced physiological …
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Development of Asset Information Requirements to support Asset Management
… of Organisational Information Requirements (OIR) and the generation of Asset Information Requirements (AIR), is too much of a jump or hurdle. This is partly due to the fact that asset management organisations purely focus on the development of technical information requirements, with little …
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Institutional Researchers and Equitable Outcomes: An Examination of Factors Driving Their Success
… posits that Offices of Institutional Research (OIR) are also critical in addressing and closing equity gaps. Through interviews with current and former institutional researchers (n=21), this qualitative case study identified environmental influences associated with institutional researchers' …
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Role of ephrinB2 and EphB4 in mouse retinal angiogenesis
… the murine model of oxygen induced retinopathy (OIR). Retinal whole mounts were prepared after fluorescein-dextran perfusion and neovascularization features were quantified in a blinded fashion. The criteria taken into account were blood vessel tuft formation, extraretinal neovascularization, …
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Discoveries of Targets and Novel Agents for the Treatment of Ischemic Retinopathy and Neovascular Disease
… RNV in the murine oxygen-induced retinopathy (OIR) model. </p> <p>Targeting stress kinase activation of FA signaling post-IR injury served as a way to prevent the pathological progression of RNV, <em>in vivo. </em>However, it is difficult to predict when or how to treat the inflammation early …
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Selección de grandes productores de fruto de Pinus pinea L. en la meseta norte
… modelo de regrasión establecido explica un 58 oir cuebti de la produción , atribuyendo un 46 por ciento a factores externos-en particular la suma de precipitaciones de enero a mayo del añode la floración -y el resto a la carga de piña en el momento de la inducción floral.El ajuste de las …