Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"OCT1"”.
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STRUCTURAL INSIGHTS INTO RNA POLYMERASE III PRE-INITIATION COMPLEX AND THE PIONEER ROLE OF OCT1
… higher eukaryotes. In parallel, we investigated OCT1 (POU2F1), a transcription factor known to bind distal sequence elements (DSEs) upstream of Class III Pol III promoters. Although widely expressed and implicated in gene regulation, OCT1’s potential role as a pioneer transcription factor has not …
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Pharmacokinetics and Biological Mechanisms of Drug Outcomes in Type 2 Diabetes Mellitus
… crossover study to determine the impact of OCT1 genotype and the use of OCT1 inhibiting drugs on metformin intolerance, has identified a significant gene*drug interaction between OCT1, metformin and omeprazole. The study data show that individuals with OCT1 wild type have improved tolerance …
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Funktion von BOB.1/OBF.1 für oktamerabhängige und Immunglobulin-Transkription in B-Zellen und Hodgkin-Reed-Sternberg-Zellen und Identifizierung von BOB.1/OBF.1-regulierten Genen
… transkriptioneller Koaktivator. Er bindet an die Oct1 und Oct2 Transkriptionsfaktoren und verstärkt deren transkriptionelles Potential. Die Untersuchung BOB.1/OBF.1- defizienter Mäuse ergab, dass BOB.1/OBF.1 eine entscheidende Funktion hat in verschiedenen BZellentwicklungsstadien. …
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THE INTERACTION OF TRANSCRIPTION FACTORS WITH THE LONG CONTROL REGION OF HPV 16
… functionally relevant since only NFA but not Oct1 binds a related motif in different papillomaviruses. A comparison of t11ese findings with the genomes and transcription factor binding sites of HPV 6, 11, 18, 31 and 33 led to the proposal that - in spite of a lack of a significant amount of …
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Analysis of B lymphocyte activation and differentiation by expression profiling
… Ly-6A/E, TAF10, SLFN1, SLFN2, CalA, CCR2 and Oct1 might be potential EGR1 target genes in B cells. Ly-6D and Ly-6E are upregulated in both EGRxSLP65-/- and SLP65-/- B cells, since the cells are T1 and T2 B cells. We also could show that IRF1 is downregulated upon BCR cross-linking in SLP65-/- …