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Showing 1 to 5 of 5 for “"OCA-B"”.

  1. The Dual Role of OCA-B in B Cell Development and Signaling

    Siegel, Rachael

    <p>OCA-B (Oct coactivator from B cells) is a B-cell specific coactivator of transcription that acts in conjunction with the ubiquitously expressed activator, OCT-1 or the B cell-restricted OCT-2. OCT-1 or OCT-2 can bind an upstream octamer element with the consensus sequence 5'-ATGCAAAT-3' in …

    rockefeller Repository record

  2. Old protein, new perspective : the role of Oct-1 during embryonic development and lymphopoiesis

    Wang, Victoria Elizabeth, 1973-Massachusetts Institute of Technology2003

    … for Oct-2 and the B cell specific coactivator OCA-B/OBF-1/Bob-1 but these experiments were complicated by the presence of Oct-1 in the cells. In order to understand the degree of functional redundancy shared by homologous members of this family, a genetic model of Oct-i was created using gene …

    mit Repository record

  3. Der Einfluss von NF-kB auf die Expression des Transkriptionscoaktivators BOB.1/OBF.1

    Kilzheimer, MelanieUniversität Ulm

    ulm-diss Repository record

  4. Targeting essential germinal centre transcriptional programmes in B cell lymphoma

    Runge, HendrikUniversity of Cambridge2022

    [Restricted]

    cambridge Repository record

  5. Regulation der BOB.1/OBF.1-Expression und der BOB.1/OBF.1-Proteinstabilität

    Böhm, JannicUniversität Würzburg

    Der transkriptionelle Koaktivator BOB.1/OBF.1 spielt eine wichtige Rolle in der oktamer-abhängigen Transkription in B-Lymphozyten. Mäuse, denen dieser Koaktivator fehlt, zeigen verschiedene Defekte in der B-Zellentwicklung. Besonders auffällig ist hierbei das völlige Fehlen der Keimzentren. …

    wurz-thes Repository record