Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"O'Brien-Fleming"”.
-
Evaluating Alpha Spending Functions Applied to Observational Time-to-Event Analysis
… compares the performance of the Pocock and O’Brien-Fleming alpha spending functions, revealing that the Pocock method can become highly conservative under conditions of high censoring or small sample sizes. Third, the results provide insight into sample size requirements necessary to maintain …