Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Nxf3"”.
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Evolutionary conservation of unistrand piRNA clusters and characterisation of the piRNA precursor export machinery in Drosophila
… process hinges on the nuclear export factor Nxf3, its co-factor Nxt1, and the orphan protein Bootlegger (Boot). Through interaction studies, I established that Boot and Nxf3 are multivalent interaction partners. Orthogonally, XL-MS data indicates that there are interacting residues between …
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Determinants of piRNA precursor transcription and export in Drosophila melanogaster
… Drosophila Nuclear export factor family protein Nxf3. Nxf3 is recruited to piRNA clusters by Bootlegger, a novel piRNA factor characterised in this work. Nxf3 specifically binds piRNA cluster transcripts and is responsible for their export to peri-nuclear processing sites via a Crm1-dependent …
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The role of human and Drosophila NXF proteins in nuclear mRNA export
… mRNA in vivo. Using these assays, human NXF2, NXF3 and NXF5 were all shown to interact with the known NXF partner p15. NXF2 and NXF5 were also found to bind directly to RNA, but only NXF2 was able to bind directly to nucleoporins and to promote the nuclear export of an (untethered) reporter …