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Showing 1 to 1 of 1 for “"Nucleotide exchage factor"”.
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The Role of BiP Nucleotide Exchange Factor Sil1 in Immunoglobulin Biosynthesis
… members, cycles of BiP binding and release are nucleotide dependent and facilitated by two genres of cochaperones, HSP40s, and nucleotide exchange factors (NEFs). HSP40s function in stimulating the hydrolysis of ATP, which causes a conformational change that induces tight binding of BiP to …